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Pathogen-specific B-cell receptors drive chronic lymphocytic leukemia by light-chain-dependent cross-reaction with autoantigens.
Jiménez de Oya, Nereida; De Giovanni, Marco; Fioravanti, Jessica; Übelhart, Rudolf; Di Lucia, Pietro; Fiocchi, Amleto; Iacovelli, Stefano; Efremov, Dimitar G; Caligaris-Cappio, Federico; Jumaa, Hassan; Ghia, Paolo; Guidotti, Luca G; Iannacone, Matteo.
Affiliation
  • Jiménez de Oya N; Division of Immunology, Transplantation and Infectious Diseases, IRCCS San Raffaele Scientific Institute, Milan, Italy.
  • De Giovanni M; Division of Immunology, Transplantation and Infectious Diseases, IRCCS San Raffaele Scientific Institute, Milan, Italy.
  • Fioravanti J; Vita-Salute San Raffaele University, Milan, Italy.
  • Übelhart R; Division of Immunology, Transplantation and Infectious Diseases, IRCCS San Raffaele Scientific Institute, Milan, Italy.
  • Di Lucia P; Institute of Immunology, University Hospital Ulm, Ulm, Germany.
  • Fiocchi A; Division of Immunology, Transplantation and Infectious Diseases, IRCCS San Raffaele Scientific Institute, Milan, Italy.
  • Iacovelli S; Division of Immunology, Transplantation and Infectious Diseases, IRCCS San Raffaele Scientific Institute, Milan, Italy.
  • Efremov DG; Molecular Hematology Unit, International Centre for Genetic Engineering & Biotechnology, Trieste, Italy.
  • Caligaris-Cappio F; Molecular Hematology Unit, International Centre for Genetic Engineering & Biotechnology, Trieste, Italy.
  • Jumaa H; Division of Experimental Oncology, IRCCS San Raffaele Scientific Institute, Milan, Italy.
  • Ghia P; Institute of Immunology, University Hospital Ulm, Ulm, Germany.
  • Guidotti LG; Department of Molecular Immunology, Faculty of Biology, Albert-Ludwigs University of Freiburg, Freiburg, Germany.
  • Iannacone M; Vita-Salute San Raffaele University, Milan, Italy.
EMBO Mol Med ; 9(11): 1482-1490, 2017 11.
Article in En | MEDLINE | ID: mdl-28899929
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Autoantigens / Receptors, Antigen, B-Cell / Leukemia, Lymphocytic, Chronic, B-Cell / Proto-Oncogene Proteins Limits: Animals Language: En Journal: EMBO Mol Med Journal subject: BIOLOGIA MOLECULAR Year: 2017 Document type: Article Affiliation country:
Fulltext
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Print
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PubMed Links
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Autoantigens / Receptors, Antigen, B-Cell / Leukemia, Lymphocytic, Chronic, B-Cell / Proto-Oncogene Proteins Limits: Animals Language: En Journal: EMBO Mol Med Journal subject: BIOLOGIA MOLECULAR Year: 2017 Document type: Article Affiliation country: