[Acute-on-chronic liver failure].
Ugeskr Laeger
; 179(38)2017 Sep 18.
Article
in Da
| MEDLINE
| ID: mdl-28918795
ABSTRACT
Acute-on-chronic liver failure (ACLF) is a clinical syndrome characterized by acute decompensation of liver cirrhosis, organ failure and high short-term mortality (20-80% at one month). The main precipitants are infections and excessive alcohol intake, and the mechanistic features include a high level of systemic inflammation, macrophage activation and liver injury. The severity of ACLF is graded according to the number and extent of organ failures. Prognostic scores help predict mortality and support decisions on intensive treatment or futility.
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Collection:
01-internacional
Database:
MEDLINE
Main subject:
Acute-On-Chronic Liver Failure
Type of study:
Etiology_studies
/
Prognostic_studies
Limits:
Humans
Language:
Da
Journal:
Ugeskr Laeger
Year:
2017
Document type:
Article