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Safety and immunogenicity of a recombinant Plasmodium falciparum AMA1-DiCo malaria vaccine adjuvanted with GLA-SE or Alhydrogel® in European and African adults: A phase 1a/1b, randomized, double-blind multi-centre trial.
Sirima, S B; Durier, C; Kara, L; Houard, S; Gansane, A; Loulergue, P; Bahuaud, M; Benhamouda, N; Nebié, I; Faber, B; Remarque, E; Launay, O.
Affiliation
  • Sirima SB; Centre National de Recherche et de Formation sur le Paludisme (CNRFP), Ouagadougou, Burkina Faso.
  • Durier C; INSERM SC10-US19, Villejuif, France.
  • Kara L; INSERM CIC 1417, F-CRIN, I-REIVAC, Paris, France; Assistance Publique -Hôpitaux de Paris (AP HP), Hôpital Cochin, CIC Cochin-Pasteur, Paris, France.
  • Houard S; European Vaccine Initiative (EVI), Heidelberg, Germany.
  • Gansane A; Centre National de Recherche et de Formation sur le Paludisme (CNRFP), Ouagadougou, Burkina Faso.
  • Loulergue P; INSERM CIC 1417, F-CRIN, I-REIVAC, Paris, France; Assistance Publique -Hôpitaux de Paris (AP HP), Hôpital Cochin, CIC Cochin-Pasteur, Paris, France.
  • Bahuaud M; AP HP, Hôpital Cochin, Plateforme d'immuno-monitoring vaccinal, Laboratoire d'Immunologie, Paris, France.
  • Benhamouda N; INSERM U970, Paris, France; AP-HP, Hôpital Européen Georges Pompidou, Service d'Immunologie Biologique, Paris, France.
  • Nebié I; Centre National de Recherche et de Formation sur le Paludisme (CNRFP), Ouagadougou, Burkina Faso.
  • Faber B; Department of Parasitology, Biomedical Primate Research Centre, Rijswijk, The Netherlands.
  • Remarque E; Department of Parasitology, Biomedical Primate Research Centre, Rijswijk, The Netherlands.
  • Launay O; INSERM CIC 1417, F-CRIN, I-REIVAC, Paris, France; Assistance Publique -Hôpitaux de Paris (AP HP), Hôpital Cochin, CIC Cochin-Pasteur, Paris, France; Université Paris Descartes; Sorbonne Paris-Cité, Paris, France. Electronic address: odile.launay@aphp.fr.
Vaccine ; 35(45): 6218-6227, 2017 10 27.
Article in En | MEDLINE | ID: mdl-28947345
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Plasmodium falciparum / Protozoan Proteins / Adjuvants, Immunologic / Malaria Vaccines / Immunogenicity, Vaccine / Membrane Proteins / Antigens, Protozoan Type of study: Clinical_trials Limits: Adult / Female / Humans / Male Country/Region as subject: Africa / Europa Language: En Journal: Vaccine Year: 2017 Document type: Article Affiliation country: Country of publication:
Fulltext
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Plasmodium falciparum / Protozoan Proteins / Adjuvants, Immunologic / Malaria Vaccines / Immunogenicity, Vaccine / Membrane Proteins / Antigens, Protozoan Type of study: Clinical_trials Limits: Adult / Female / Humans / Male Country/Region as subject: Africa / Europa Language: En Journal: Vaccine Year: 2017 Document type: Article Affiliation country: Country of publication: