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Intratumoural evolutionary landscape of high-risk prostate cancer: the PROGENY study of genomic and immune parameters.
Linch, M; Goh, G; Hiley, C; Shanmugabavan, Y; McGranahan, N; Rowan, A; Wong, Y N S; King, H; Furness, A; Freeman, A; Linares, J; Akarca, A; Herrero, J; Rosenthal, R; Harder, N; Schmidt, G; Wilson, G A; Birkbak, N J; Mitter, R; Dentro, S; Cathcart, P; Arya, M; Johnston, E; Scott, R; Hung, M; Emberton, M; Attard, G; Szallasi, Z; Punwani, S; Quezada, S A; Marafioti, T; Gerlinger, M; Ahmed, H U; Swanton, C.
Affiliation
  • Linch M; Translational Cancer Therapeutics Laboratory, UCL Cancer Institute, London, UK;; Department of Medical Oncology, University College London Hospitals NHS Foundation Trust, London, UK.
  • Goh G; Translational Cancer Therapeutics Laboratory, UCL Cancer Institute, London, UK;; Bill Lyons Informatics Centre, UCL Cancer Institute, London, UK.
  • Hiley C; Division of Cancer Studies, King's College London, London, UK;; Translational Cancer Therapeutics Laboratory, The Francis Crick Institute, London, UK.
  • Shanmugabavan Y; Division of Surgery and Interventional Science, University College London, London, UK.
  • McGranahan N; Translational Cancer Therapeutics Laboratory, UCL Cancer Institute, London, UK;; Translational Cancer Therapeutics Laboratory, The Francis Crick Institute, London, UK.
  • Rowan A; Translational Cancer Therapeutics Laboratory, The Francis Crick Institute, London, UK.
  • Wong YNS; Translational Cancer Therapeutics Laboratory, UCL Cancer Institute, London, UK;; Cancer Immunology Unit, UCL Cancer Institute, London, UK;; Research Department of Haematology, UCL Cancer Institute, London, UK.
  • King H; Translational Cancer Therapeutics Laboratory, UCL Cancer Institute, London, UK.
  • Furness A; Cancer Immunology Unit, UCL Cancer Institute, London, UK;; Research Department of Haematology, UCL Cancer Institute, London, UK.
  • Freeman A; Department of Histopathology, University College London Hospitals NHS Foundation Trust, London, UK.
  • Linares J; Department of Histopathology, University College London Hospitals NHS Foundation Trust, London, UK.
  • Akarca A; Department of Histopathology, University College London Hospitals NHS Foundation Trust, London, UK.
  • Herrero J; Bill Lyons Informatics Centre, UCL Cancer Institute, London, UK.
  • Rosenthal R; Translational Cancer Therapeutics Laboratory, UCL Cancer Institute, London, UK;; Bill Lyons Informatics Centre, UCL Cancer Institute, London, UK.
  • Harder N; Definiens AG, Munich, Germany.
  • Schmidt G; Definiens AG, Munich, Germany.
  • Wilson GA; Translational Cancer Therapeutics Laboratory, UCL Cancer Institute, London, UK;; Translational Cancer Therapeutics Laboratory, The Francis Crick Institute, London, UK.
  • Birkbak NJ; Translational Cancer Therapeutics Laboratory, UCL Cancer Institute, London, UK;; Translational Cancer Therapeutics Laboratory, The Francis Crick Institute, London, UK.
  • Mitter R; Department of Bioinformatics and Biostatistics, The Francis Crick Institute, London, UK.
  • Dentro S; Cancer Genomics Laboratory, The Francis Crick Institute, London, UK;; Experimental Cancer Genetics, Wellcome Trust Sanger Institute, Cambridge, UK.
  • Cathcart P; The Urology Centre, Guy's and St. Thomas' NHS Foundation Trust, London, UK.
  • Arya M; Division of Surgery and Interventional Science, University College London, London, UK;; Department of Urology, UCLH NHS Foundation Trust, London, UK.
  • Johnston E; Centre for Medical Imaging, Universtiy College London, London, UK.
  • Scott R; Division of Surgery and Interventional Science, University College London, London, UK.
  • Hung M; Division of Surgery and Interventional Science, University College London, London, UK.
  • Emberton M; Division of Surgery and Interventional Science, University College London, London, UK;; Department of Urology, UCLH NHS Foundation Trust, London, UK.
  • Attard G; Centre for Evolution and Cancer, The Institute of Cancer Research, London, UK;; Department of Medical Oncology, Royal Marsden Hospital, London, UK.
  • Szallasi Z; Centre for Biological Sequence Analysis, Technical University of Denmark, Lyngby, Denmark;; Computational Health Informatics Program (CHIP), Harvard Medical School, Boston, USA;; MTA-SE-NAP Brain Metastasis Research Group, Semmelweis University, Budapest, Hungary.
  • Punwani S; Centre for Medical Imaging, Universtiy College London, London, UK.
  • Quezada SA; Cancer Immunology Unit, UCL Cancer Institute, London, UK;; Research Department of Haematology, UCL Cancer Institute, London, UK.
  • Marafioti T; Department of Histopathology, University College London Hospitals NHS Foundation Trust, London, UK.
  • Gerlinger M; Centre for Evolution and Cancer, The Institute of Cancer Research, London, UK;; Department of Medical Oncology, Royal Marsden Hospital, London, UK.
  • Ahmed HU; Division of Surgery and Interventional Science, University College London, London, UK;; Division of Surgery, Department of Surgery and Cancer, Imperial College London, UK;; Department of Urology, Imperial College Healthcare NHS Trust, London, UK. Electronic address: hashim.ahmed@imperial.ac.uk.
  • Swanton C; Translational Cancer Therapeutics Laboratory, UCL Cancer Institute, London, UK;; Department of Medical Oncology, University College London Hospitals NHS Foundation Trust, London, UK;; Translational Cancer Therapeutics Laboratory, The Francis Crick Institute, London, UK;. Electronic address: charles.
Ann Oncol ; 28(10): 2472-2480, 2017 Oct 01.
Article in En | MEDLINE | ID: mdl-28961847
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Prostatic Neoplasms Type of study: Etiology_studies / Prognostic_studies / Risk_factors_studies Limits: Humans / Male Language: En Journal: Ann Oncol Journal subject: NEOPLASIAS Year: 2017 Document type: Article Affiliation country:
Fulltext
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Prostatic Neoplasms Type of study: Etiology_studies / Prognostic_studies / Risk_factors_studies Limits: Humans / Male Language: En Journal: Ann Oncol Journal subject: NEOPLASIAS Year: 2017 Document type: Article Affiliation country: