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The homeodomain-interacting protein kinase HPK-1 preserves protein homeostasis and longevity through master regulatory control of the HSF-1 chaperone network and TORC1-restricted autophagy in Caenorhabditis elegans.
Das, Ritika; Melo, Justine A; Thondamal, Manjunatha; Morton, Elizabeth A; Cornwell, Adam B; Crick, Beresford; Kim, Joung Heon; Swartz, Elliot W; Lamitina, Todd; Douglas, Peter M; Samuelson, Andrew V.
Affiliation
  • Das R; Department of Biomedical Genetics, University of Rochester Medical Center, Rochester, New York, United States of America.
  • Melo JA; Department of Biology, University of Rochester, Rochester, New York, United States of America.
  • Thondamal M; Department of Biomedical Genetics, University of Rochester Medical Center, Rochester, New York, United States of America.
  • Morton EA; Department of Biomedical Genetics, University of Rochester Medical Center, Rochester, New York, United States of America.
  • Cornwell AB; Department of Genome Sciences, University of Washington, Seattle, Washington, United States of America.
  • Crick B; Department of Biomedical Genetics, University of Rochester Medical Center, Rochester, New York, United States of America.
  • Kim JH; Department of Biomedical Genetics, University of Rochester Medical Center, Rochester, New York, United States of America.
  • Swartz EW; Department of Biomedical Genetics, University of Rochester Medical Center, Rochester, New York, United States of America.
  • Lamitina T; Department of Biomedical Genetics, University of Rochester Medical Center, Rochester, New York, United States of America.
  • Douglas PM; Department of Cell Biology, University of Pittsburgh, Pittsburgh, Pennsylvania, United States of America.
  • Samuelson AV; Department of Molecular Biology, Hamon Center for Regenerative Science and Medicine, UT Southwestern Medical Center, Dallas, Texas, United States of America.
PLoS Genet ; 13(10): e1007038, 2017 Oct.
Article in En | MEDLINE | ID: mdl-29036198

Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Transcription Factors / Aging / Protein Serine-Threonine Kinases / Caenorhabditis elegans Proteins / Multiprotein Complexes / TOR Serine-Threonine Kinases / Longevity Limits: Animals Language: En Journal: PLoS Genet Journal subject: GENETICA Year: 2017 Document type: Article Affiliation country:

Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Transcription Factors / Aging / Protein Serine-Threonine Kinases / Caenorhabditis elegans Proteins / Multiprotein Complexes / TOR Serine-Threonine Kinases / Longevity Limits: Animals Language: En Journal: PLoS Genet Journal subject: GENETICA Year: 2017 Document type: Article Affiliation country: