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Efficacy of NVR 3-778, Alone and In Combination With Pegylated Interferon, vs Entecavir In uPA/SCID Mice With Humanized Livers and HBV Infection.
Klumpp, Klaus; Shimada, Takashi; Allweiss, Lena; Volz, Tassilo; Lütgehetmann, Marc; Hartman, George; Flores, Osvaldo A; Lam, Angela M; Dandri, Maura.
Affiliation
  • Klumpp K; Novira Therapeutics Inc, part of the Janssen Pharmaceutical Companies, Doylestown, Pennsylvania. Electronic address: klausgklumpp@gmail.com.
  • Shimada T; PhoenixBio Co., Ltd., Higashi-Hiroshima, Japan.
  • Allweiss L; I. Department of Internal Medicine, University Medical Center Hamburg-Eppendorf, Hamburg, Germany.
  • Volz T; I. Department of Internal Medicine, University Medical Center Hamburg-Eppendorf, Hamburg, Germany.
  • Lütgehetmann M; I. Department of Internal Medicine, University Medical Center Hamburg-Eppendorf, Hamburg, Germany; Institute of Microbiology, Virology and Hygiene, University Medical Center Hamburg-Eppendorf, Hamburg, Germany.
  • Hartman G; Novira Therapeutics Inc, part of the Janssen Pharmaceutical Companies, Doylestown, Pennsylvania.
  • Flores OA; Novira Therapeutics Inc, part of the Janssen Pharmaceutical Companies, Doylestown, Pennsylvania.
  • Lam AM; Novira Therapeutics Inc, part of the Janssen Pharmaceutical Companies, Doylestown, Pennsylvania.
  • Dandri M; I. Department of Internal Medicine, University Medical Center Hamburg-Eppendorf, Hamburg, Germany; German Center for Infection Research, Hamburg-Lübeck-Borstel Partner Site, Germany.
Gastroenterology ; 154(3): 652-662.e8, 2018 02.
Article in En | MEDLINE | ID: mdl-29079518
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Antiviral Agents / Polyethylene Glycols / Urokinase-Type Plasminogen Activator / Hepatitis B virus / Interferon-alpha / Hepatocytes / Guanine / Hepatitis B Type of study: Diagnostic_studies / Prognostic_studies Limits: Animals / Humans Language: En Journal: Gastroenterology Year: 2018 Document type: Article
Fulltext
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Antiviral Agents / Polyethylene Glycols / Urokinase-Type Plasminogen Activator / Hepatitis B virus / Interferon-alpha / Hepatocytes / Guanine / Hepatitis B Type of study: Diagnostic_studies / Prognostic_studies Limits: Animals / Humans Language: En Journal: Gastroenterology Year: 2018 Document type: Article