Effect of maltitol-containing chewing gum use on the composition of dental plaque microbiota in subjects with active dental caries.
J Oral Microbiol
; 9(1): 1374152, 2017.
Article
in En
| MEDLINE
| ID: mdl-29081913
ABSTRACT
Background:
Sugar alcohols such as xylitol are incorporated in a number of oral hygiene products for their anti-cariogenic properties while chewing gum is known to be beneficial to oral hygiene.Objective:
The aim of this study was to determine the composition of the dental plaque microbiota in patients with active caries before and after using a chewing gum supplemented with maltitol.Design:
Forty subjects with active caries were randomly allocated to chew maltitol gum or gum base for two weeks. A healthy control group used gum base for two weeks. Plaque samples were collected before and after treatment and the microbiota analysed by pyrosequencing of 16S rRNA genes.Results:
A total of 773,547 sequences were obtained from 117 samples. There was no difference in structure of the bacterial communities between groups (AMOVA). There was a significant difference in community membership between groups, (AMOVA, p=0.009). There was a significant difference between the control group after treatment and the maltitol patient group after treatment (p<0.001). A. naeslundii HOT-176 and Actinomyces HOT-169 were significantly reduced following use of maltitol chewing gum in patients.Conclusions:
This study has shown that chewing gum containing maltitol had minor effects on the composition of the plaque microbiome.
Full text:
1
Collection:
01-internacional
Database:
MEDLINE
Language:
En
Journal:
J Oral Microbiol
Year:
2017
Document type:
Article
Affiliation country: