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Genomic Subtypes of Non-invasive Bladder Cancer with Distinct Metabolic Profile and Female Gender Bias in KDM6A Mutation Frequency.
Hurst, Carolyn D; Alder, Olivia; Platt, Fiona M; Droop, Alastair; Stead, Lucy F; Burns, Julie E; Burghel, George J; Jain, Sunjay; Klimczak, Leszek J; Lindsay, Helen; Roulson, Jo-An; Taylor, Claire F; Thygesen, Helene; Cameron, Angus J; Ridley, Anne J; Mott, Helen R; Gordenin, Dmitry A; Knowles, Margaret A.
Affiliation
  • Hurst CD; Section of Molecular Oncology, Leeds Institute of Cancer and Pathology, St James's University Hospital, Beckett Street, Leeds LS9 7TF, UK.
  • Alder O; Section of Molecular Oncology, Leeds Institute of Cancer and Pathology, St James's University Hospital, Beckett Street, Leeds LS9 7TF, UK.
  • Platt FM; Section of Molecular Oncology, Leeds Institute of Cancer and Pathology, St James's University Hospital, Beckett Street, Leeds LS9 7TF, UK.
  • Droop A; Cancer Research UK Leeds Centre, Leeds Institute of Cancer and Pathology, St James's University Hospital, Beckett Street, Leeds LS9 7TF, UK.
  • Stead LF; Section of Brain Tumour Research, Leeds Institute of Cancer and Pathology, St James's University Hospital, Beckett Street, Leeds LS9 7TF, UK.
  • Burns JE; Section of Molecular Oncology, Leeds Institute of Cancer and Pathology, St James's University Hospital, Beckett Street, Leeds LS9 7TF, UK.
  • Burghel GJ; DNA Laboratory, Genetics Service, Ashley Wing, St James University Hospital, Beckett Street, Leeds LS9 7TF, UK.
  • Jain S; Pyrah Department of Urology, St James's University Hospital, Beckett Street, Leeds LS9 7TF, UK.
  • Klimczak LJ; Integrative Bioinformatics Support Group, National Institute of Environmental Health Sciences, NIH, Research Triangle Park, NC 27709, USA.
  • Lindsay H; DNA Laboratory, Genetics Service, Ashley Wing, St James University Hospital, Beckett Street, Leeds LS9 7TF, UK.
  • Roulson JA; Department of Histopathology, St James's University Hospital, Beckett Street, Leeds LS9 7TF, UK.
  • Taylor CF; Cancer Research UK Leeds Centre, Leeds Institute of Cancer and Pathology, St James's University Hospital, Beckett Street, Leeds LS9 7TF, UK.
  • Thygesen H; Cancer Research UK Leeds Centre, Leeds Institute of Cancer and Pathology, St James's University Hospital, Beckett Street, Leeds LS9 7TF, UK.
  • Cameron AJ; Barts Cancer Institute, Queen Mary University of London, Charterhouse Square, London EC1M 6BQ, UK.
  • Ridley AJ; Randall Division of Cell and Molecular Biophysics, New Hunt's House, King's College London, Guy's Campus, London SE1 1UL, UK.
  • Mott HR; Department of Biochemistry, University of Cambridge, 80 Tennis Court Road, Cambridge CB2 1GA, UK.
  • Gordenin DA; Genome Integrity and Structural Biology Laboratory, National Institute of Environmental Health Sciences, NIH, Research Triangle Park, NC 27709, USA.
  • Knowles MA; Section of Molecular Oncology, Leeds Institute of Cancer and Pathology, St James's University Hospital, Beckett Street, Leeds LS9 7TF, UK. Electronic address: m.a.knowles@leeds.ac.uk.
Cancer Cell ; 32(5): 701-715.e7, 2017 11 13.
Article in En | MEDLINE | ID: mdl-29136510
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Urinary Bladder Neoplasms / Nuclear Proteins / Carcinoma, Transitional Cell / Metabolomics / Histone Demethylases / Mutation Type of study: Prognostic_studies Aspects: Determinantes_sociais_saude Limits: Female / Humans / Male Language: En Journal: Cancer Cell Journal subject: NEOPLASIAS Year: 2017 Document type: Article Affiliation country:
Fulltext
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Urinary Bladder Neoplasms / Nuclear Proteins / Carcinoma, Transitional Cell / Metabolomics / Histone Demethylases / Mutation Type of study: Prognostic_studies Aspects: Determinantes_sociais_saude Limits: Female / Humans / Male Language: En Journal: Cancer Cell Journal subject: NEOPLASIAS Year: 2017 Document type: Article Affiliation country: