Theophylline as an adjunct to control malignant ventricular arrhythmia associated with early repolarization.
Pacing Clin Electrophysiol
; 41(5): 444-446, 2018 05.
Article
in En
| MEDLINE
| ID: mdl-29148059
ABSTRACT
Early repolarization (ER) has been associated with an increased risk of sudden cardiac arrest. Interestingly, ventricular arrhythmias seem to be triggered by parasympathetic stimulation. In the present case report, we describe complete control of highly frequent malignant ventricular arrhythmias after adding theophylline to ineffective oral hydroquinidine and high-rate pacing in a patient suffering from malignant ER. We hypothesize that the theophylline-mediated enhanced beta-adrenergic stimulation could reduce the transmural myocardial voltage discrepancy by increasing the inward ICa,L current.
Key words
Full text:
1
Collection:
01-internacional
Database:
MEDLINE
Main subject:
Theophylline
/
Vasodilator Agents
/
Tachycardia, Ventricular
/
Defibrillators, Implantable
Type of study:
Risk_factors_studies
Limits:
Child
/
Humans
/
Male
Language:
En
Journal:
Pacing Clin Electrophysiol
Year:
2018
Document type:
Article
Affiliation country: