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Structure of Rap1b bound to talin reveals a pathway for triggering integrin activation.
Zhu, Liang; Yang, Jun; Bromberger, Thomas; Holly, Ashley; Lu, Fan; Liu, Huan; Sun, Kevin; Klapproth, Sarah; Hirbawi, Jamila; Byzova, Tatiana V; Plow, Edward F; Moser, Markus; Qin, Jun.
Affiliation
  • Zhu L; Department of Molecular Cardiology, Lerner Research Institute, Cleveland Clinic, 9500 Euclid Avenue, Cleveland, OH, 44195, USA.
  • Yang J; Department of Biochemistry, Case Western Reserve University, Cleveland, OH, 44106, USA.
  • Bromberger T; Department of Molecular Cardiology, Lerner Research Institute, Cleveland Clinic, 9500 Euclid Avenue, Cleveland, OH, 44195, USA.
  • Holly A; Max-Planck-Institute of Biochemistry, Department of Molecular Medicine, 82152, Martinsried, Germany.
  • Lu F; Department of Molecular Cardiology, Lerner Research Institute, Cleveland Clinic, 9500 Euclid Avenue, Cleveland, OH, 44195, USA.
  • Liu H; Department of Molecular Cardiology, Lerner Research Institute, Cleveland Clinic, 9500 Euclid Avenue, Cleveland, OH, 44195, USA.
  • Sun K; Department of Biochemistry, Case Western Reserve University, Cleveland, OH, 44106, USA.
  • Klapproth S; Department of Molecular Cardiology, Lerner Research Institute, Cleveland Clinic, 9500 Euclid Avenue, Cleveland, OH, 44195, USA.
  • Hirbawi J; Department of Molecular Cardiology, Lerner Research Institute, Cleveland Clinic, 9500 Euclid Avenue, Cleveland, OH, 44195, USA.
  • Byzova TV; Max-Planck-Institute of Biochemistry, Department of Molecular Medicine, 82152, Martinsried, Germany.
  • Plow EF; Department of Molecular Cardiology, Lerner Research Institute, Cleveland Clinic, 9500 Euclid Avenue, Cleveland, OH, 44195, USA.
  • Moser M; Department of Molecular Cardiology, Lerner Research Institute, Cleveland Clinic, 9500 Euclid Avenue, Cleveland, OH, 44195, USA.
  • Qin J; Department of Molecular Cardiology, Lerner Research Institute, Cleveland Clinic, 9500 Euclid Avenue, Cleveland, OH, 44195, USA.
Nat Commun ; 8(1): 1744, 2017 11 23.
Article in En | MEDLINE | ID: mdl-29170462

Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Integrins / Talin / Rap GTP-Binding Proteins Limits: Animals / Humans Language: En Journal: Nat Commun Journal subject: BIOLOGIA / CIENCIA Year: 2017 Document type: Article Affiliation country:

Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Integrins / Talin / Rap GTP-Binding Proteins Limits: Animals / Humans Language: En Journal: Nat Commun Journal subject: BIOLOGIA / CIENCIA Year: 2017 Document type: Article Affiliation country: