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The target landscape of clinical kinase drugs.
Klaeger, Susan; Heinzlmeir, Stephanie; Wilhelm, Mathias; Polzer, Harald; Vick, Binje; Koenig, Paul-Albert; Reinecke, Maria; Ruprecht, Benjamin; Petzoldt, Svenja; Meng, Chen; Zecha, Jana; Reiter, Katrin; Qiao, Huichao; Helm, Dominic; Koch, Heiner; Schoof, Melanie; Canevari, Giulia; Casale, Elena; Depaolini, Stefania Re; Feuchtinger, Annette; Wu, Zhixiang; Schmidt, Tobias; Rueckert, Lars; Becker, Wilhelm; Huenges, Jan; Garz, Anne-Kathrin; Gohlke, Bjoern-Oliver; Zolg, Daniel Paul; Kayser, Gian; Vooder, Tonu; Preissner, Robert; Hahne, Hannes; Tõnisson, Neeme; Kramer, Karl; Götze, Katharina; Bassermann, Florian; Schlegl, Judith; Ehrlich, Hans-Christian; Aiche, Stephan; Walch, Axel; Greif, Philipp A; Schneider, Sabine; Felder, Eduard Rudolf; Ruland, Juergen; Médard, Guillaume; Jeremias, Irmela; Spiekermann, Karsten; Kuster, Bernhard.
Affiliation
  • Klaeger S; Chair of Proteomics and Bioanalytics, Technical University of Munich (TUM), Freising, Germany.
  • Heinzlmeir S; German Cancer Consortium (DKTK), Heidelberg, Germany.
  • Wilhelm M; German Cancer Research Center (DKFZ), Heidelberg, Germany.
  • Polzer H; Chair of Proteomics and Bioanalytics, Technical University of Munich (TUM), Freising, Germany.
  • Vick B; German Cancer Consortium (DKTK), Heidelberg, Germany.
  • Koenig PA; German Cancer Research Center (DKFZ), Heidelberg, Germany.
  • Reinecke M; Chair of Proteomics and Bioanalytics, Technical University of Munich (TUM), Freising, Germany.
  • Ruprecht B; German Cancer Consortium (DKTK), Heidelberg, Germany.
  • Petzoldt S; German Cancer Research Center (DKFZ), Heidelberg, Germany.
  • Meng C; Department of Internal Medicine III, University Hospital, Ludwig-Maximilians-Universität (LMU) München, Munich, Germany.
  • Zecha J; German Cancer Consortium (DKTK), Heidelberg, Germany.
  • Reiter K; German Cancer Research Center (DKFZ), Heidelberg, Germany.
  • Qiao H; Department of Apoptosis in Hematopoietic Stem Cells, Helmholtz Center Munich, German Center for Environmental Health (HMGU), Munich, Germany.
  • Helm D; Institut für Klinische Chemie und Pathobiochemie, TUM, Munich, Germany.
  • Koch H; Chair of Proteomics and Bioanalytics, Technical University of Munich (TUM), Freising, Germany.
  • Schoof M; German Cancer Consortium (DKTK), Heidelberg, Germany.
  • Canevari G; German Cancer Research Center (DKFZ), Heidelberg, Germany.
  • Casale E; Chair of Proteomics and Bioanalytics, Technical University of Munich (TUM), Freising, Germany.
  • Depaolini SR; Chair of Proteomics and Bioanalytics, Technical University of Munich (TUM), Freising, Germany.
  • Feuchtinger A; German Cancer Consortium (DKTK), Heidelberg, Germany.
  • Wu Z; German Cancer Research Center (DKFZ), Heidelberg, Germany.
  • Schmidt T; Chair of Proteomics and Bioanalytics, Technical University of Munich (TUM), Freising, Germany.
  • Rueckert L; Chair of Proteomics and Bioanalytics, Technical University of Munich (TUM), Freising, Germany.
  • Becker W; German Cancer Consortium (DKTK), Heidelberg, Germany.
  • Huenges J; German Cancer Research Center (DKFZ), Heidelberg, Germany.
  • Garz AK; German Cancer Consortium (DKTK), Heidelberg, Germany.
  • Gohlke BO; German Cancer Research Center (DKFZ), Heidelberg, Germany.
  • Zolg DP; Department of Internal Medicine III, University Hospital, Ludwig-Maximilians-Universität (LMU) München, Munich, Germany.
  • Kayser G; Chair of Proteomics and Bioanalytics, Technical University of Munich (TUM), Freising, Germany.
  • Vooder T; Chair of Proteomics and Bioanalytics, Technical University of Munich (TUM), Freising, Germany.
  • Preissner R; Chair of Proteomics and Bioanalytics, Technical University of Munich (TUM), Freising, Germany.
  • Hahne H; German Cancer Consortium (DKTK), Heidelberg, Germany.
  • Tõnisson N; German Cancer Research Center (DKFZ), Heidelberg, Germany.
  • Kramer K; Chair of Proteomics and Bioanalytics, Technical University of Munich (TUM), Freising, Germany.
  • Götze K; Oncology, Nerviano Medical Sciences Srl, Milan, Italy.
  • Bassermann F; Oncology, Nerviano Medical Sciences Srl, Milan, Italy.
  • Schlegl J; Oncology, Nerviano Medical Sciences Srl, Milan, Italy.
  • Ehrlich HC; Research Unit Analytical Pathology, Helmholtz Zentrum München, Neuherberg, Germany.
  • Aiche S; Chair of Proteomics and Bioanalytics, Technical University of Munich (TUM), Freising, Germany.
  • Walch A; Chair of Proteomics and Bioanalytics, Technical University of Munich (TUM), Freising, Germany.
  • Greif PA; SAP SE, Potsdam, Germany.
  • Schneider S; SAP SE, Potsdam, Germany.
  • Felder ER; SAP SE, Potsdam, Germany.
  • Ruland J; German Cancer Consortium (DKTK), Heidelberg, Germany.
  • Médard G; German Cancer Research Center (DKFZ), Heidelberg, Germany.
  • Jeremias I; Department of Medicine III, Klinikum rechts der Isar, TUM, Munich, Germany.
  • Spiekermann K; German Cancer Consortium (DKTK), Heidelberg, Germany.
  • Kuster B; German Cancer Research Center (DKFZ), Heidelberg, Germany.
Science ; 358(6367)2017 12 01.
Article in En | MEDLINE | ID: mdl-29191878
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Proteomics / Protein Kinase Inhibitors / Drug Discovery / Molecular Targeted Therapy / Antineoplastic Agents Type of study: Prognostic_studies Limits: Animals / Humans Language: En Journal: Science Year: 2017 Document type: Article Affiliation country:
Fulltext
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Proteomics / Protein Kinase Inhibitors / Drug Discovery / Molecular Targeted Therapy / Antineoplastic Agents Type of study: Prognostic_studies Limits: Animals / Humans Language: En Journal: Science Year: 2017 Document type: Article Affiliation country: