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Antagonists of the adenosine A2A receptor based on a 2-arylbenzoxazole scaffold: Investigation of the C5- and C7-positions to enhance affinity.
Duroux, Romain; Agouridas, Laurence; Renault, Nicolas; El Bakali, Jamal; Furman, Christophe; Melnyk, Patricia; Yous, Saïd.
Affiliation
  • Duroux R; Univ. Lille, Inserm, CHU Lille, UMR-S1172 - JPArc - Centre de Recherche Jean-Pierre AUBERT Neurosciences et Cancer, F-59000 Lille, France.
  • Agouridas L; Univ. Lille, Inserm, CHU Lille, UMR-S1172 - JPArc - Centre de Recherche Jean-Pierre AUBERT Neurosciences et Cancer, F-59000 Lille, France.
  • Renault N; Univ. Lille, Inserm, CHU Lille, U995 - LIRIC - Lille Inflammation Research International Center, F-59000 Lille, France.
  • El Bakali J; Univ. Lille, Inserm, CHU Lille, UMR-S1172 - JPArc - Centre de Recherche Jean-Pierre AUBERT Neurosciences et Cancer, F-59000 Lille, France.
  • Furman C; Univ. Lille, Inserm, CHU Lille, U995 - LIRIC - Lille Inflammation Research International Center, F-59000 Lille, France.
  • Melnyk P; Univ. Lille, Inserm, CHU Lille, UMR-S1172 - JPArc - Centre de Recherche Jean-Pierre AUBERT Neurosciences et Cancer, F-59000 Lille, France.
  • Yous S; Univ. Lille, Inserm, CHU Lille, UMR-S1172 - JPArc - Centre de Recherche Jean-Pierre AUBERT Neurosciences et Cancer, F-59000 Lille, France. Electronic address: said.yous@univ-lille2.fr.
Eur J Med Chem ; 144: 151-163, 2018 Jan 20.
Article in En | MEDLINE | ID: mdl-29268131
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Benzoxazoles / Receptor, Adenosine A2A / Adenosine A2 Receptor Antagonists Limits: Humans Language: En Journal: Eur J Med Chem Year: 2018 Document type: Article Affiliation country: Country of publication:
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Benzoxazoles / Receptor, Adenosine A2A / Adenosine A2 Receptor Antagonists Limits: Humans Language: En Journal: Eur J Med Chem Year: 2018 Document type: Article Affiliation country: Country of publication: