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Angiopoietins bind thrombomodulin and inhibit its function as a thrombin cofactor.
Daly, Christopher; Qian, Xiaozhong; Castanaro, Carla; Pasnikowski, Elizabeth; Jiang, Xiabo; Thomson, Benjamin R; Quaggin, Susan E; Papadopoulos, Nicholas; Wei, Yang; Rudge, John S; Thurston, Gavin; Yancopoulos, George D; Davis, Samuel.
Affiliation
  • Daly C; Regeneron Pharmaceuticals, Inc., 777 Old Saw Mill River Road, Tarrytown, New York, 10591, USA. christopher.daly@regeneron.com.
  • Qian X; Regeneron Pharmaceuticals, Inc., 777 Old Saw Mill River Road, Tarrytown, New York, 10591, USA.
  • Castanaro C; Regeneron Pharmaceuticals, Inc., 777 Old Saw Mill River Road, Tarrytown, New York, 10591, USA.
  • Pasnikowski E; Regeneron Pharmaceuticals, Inc., 777 Old Saw Mill River Road, Tarrytown, New York, 10591, USA.
  • Jiang X; Regeneron Pharmaceuticals, Inc., 777 Old Saw Mill River Road, Tarrytown, New York, 10591, USA.
  • Thomson BR; Feinberg Cardiovascular Research Institute, Northwestern University Feinberg School of Medicine, Chicago, Illinois, USA.
  • Quaggin SE; Division of Nephrology/Hypertension, Northwestern University Feinberg School of Medicine, Chicago, Illinois, USA.
  • Papadopoulos N; Feinberg Cardiovascular Research Institute, Northwestern University Feinberg School of Medicine, Chicago, Illinois, USA.
  • Wei Y; Division of Nephrology/Hypertension, Northwestern University Feinberg School of Medicine, Chicago, Illinois, USA.
  • Rudge JS; Regeneron Pharmaceuticals, Inc., 777 Old Saw Mill River Road, Tarrytown, New York, 10591, USA.
  • Thurston G; Regeneron Pharmaceuticals, Inc., 777 Old Saw Mill River Road, Tarrytown, New York, 10591, USA.
  • Yancopoulos GD; Regeneron Pharmaceuticals, Inc., 777 Old Saw Mill River Road, Tarrytown, New York, 10591, USA.
  • Davis S; Regeneron Pharmaceuticals, Inc., 777 Old Saw Mill River Road, Tarrytown, New York, 10591, USA.
Sci Rep ; 8(1): 505, 2018 01 11.
Article in En | MEDLINE | ID: mdl-29323190
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Thrombin / Thrombomodulin / Angiopoietin-1 / Angiopoietin-2 Type of study: Prognostic_studies Limits: Animals / Humans Language: En Journal: Sci Rep Year: 2018 Document type: Article Affiliation country: Country of publication:
Fulltext
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Thrombin / Thrombomodulin / Angiopoietin-1 / Angiopoietin-2 Type of study: Prognostic_studies Limits: Animals / Humans Language: En Journal: Sci Rep Year: 2018 Document type: Article Affiliation country: Country of publication: