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The GPR120 agonist TUG-891 promotes metabolic health by stimulating mitochondrial respiration in brown fat.
Schilperoort, Maaike; van Dam, Andrea D; Hoeke, Geerte; Shabalina, Irina G; Okolo, Anthony; Hanyaloglu, Aylin C; Dib, Lea H; Mol, Isabel M; Caengprasath, Natarin; Chan, Yi-Wah; Damak, Sami; Miller, Anne Reifel; Coskun, Tamer; Shimpukade, Bharat; Ulven, Trond; Kooijman, Sander; Rensen, Patrick Cn; Christian, Mark.
Affiliation
  • Schilperoort M; Division of Biomedical Sciences, Warwick Medical School, University of Warwick, Coventry, UK m.schilperoort@lumc.nl m.christian@warwick.ac.uk.
  • van Dam AD; Division of Endocrinology, Department of Medicine, Leiden University Medical Center, Leiden, The Netherlands.
  • Hoeke G; Einthoven Laboratory for Experimental Vascular Medicine, Leiden, The Netherlands.
  • Shabalina IG; Division of Endocrinology, Department of Medicine, Leiden University Medical Center, Leiden, The Netherlands.
  • Okolo A; Einthoven Laboratory for Experimental Vascular Medicine, Leiden, The Netherlands.
  • Hanyaloglu AC; Division of Endocrinology, Department of Medicine, Leiden University Medical Center, Leiden, The Netherlands.
  • Dib LH; Einthoven Laboratory for Experimental Vascular Medicine, Leiden, The Netherlands.
  • Mol IM; Department of Molecular Biosciences, The Wenner-Gren Institute, The Arrhenius Laboratories F3, Stockholm University, Stockholm, Sweden.
  • Caengprasath N; Department of Surgery and Cancer, Institute of Reproductive and Developmental Biology, Imperial College London, London, UK.
  • Chan YW; Department of Surgery and Cancer, Institute of Reproductive and Developmental Biology, Imperial College London, London, UK.
  • Damak S; Institute of Cardiovascular Sciences, College of Medical and Dental Sciences, University of Birmingham, Birmingham, UK.
  • Miller AR; Division of Endocrinology, Department of Medicine, Leiden University Medical Center, Leiden, The Netherlands.
  • Coskun T; Einthoven Laboratory for Experimental Vascular Medicine, Leiden, The Netherlands.
  • Shimpukade B; Department of Surgery and Cancer, Institute of Reproductive and Developmental Biology, Imperial College London, London, UK.
  • Ulven T; Lymphocyte Development Group, MRC London Institute of Medical Sciences, Hammersmith Campus Imperial College London, London, UK.
  • Kooijman S; Nestlé Research Center, Lausanne, Switzerland.
  • Rensen PC; Lilly Research Laboratories, Diabetes/Endocrine Department, Lilly Corporate Center, Indianapolis, IN, USA.
  • Christian M; Lilly Research Laboratories, Diabetes/Endocrine Department, Lilly Corporate Center, Indianapolis, IN, USA.
EMBO Mol Med ; 10(3)2018 03.
Article in En | MEDLINE | ID: mdl-29343498

Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Phenylpropionates / Biphenyl Compounds / Adipose Tissue, Brown / Receptors, G-Protein-Coupled / Mitochondria Limits: Animals Language: En Journal: EMBO Mol Med Journal subject: BIOLOGIA MOLECULAR Year: 2018 Document type: Article

Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Phenylpropionates / Biphenyl Compounds / Adipose Tissue, Brown / Receptors, G-Protein-Coupled / Mitochondria Limits: Animals Language: En Journal: EMBO Mol Med Journal subject: BIOLOGIA MOLECULAR Year: 2018 Document type: Article