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Precise characterization of KRAS4b proteoforms in human colorectal cells and tumors reveals mutation/modification cross-talk.
Ntai, Ioanna; Fornelli, Luca; DeHart, Caroline J; Hutton, Josiah E; Doubleday, Peter F; LeDuc, Richard D; van Nispen, Alexandra J; Fellers, Ryan T; Whiteley, Gordon; Boja, Emily S; Rodriguez, Henry; Kelleher, Neil L.
Affiliation
  • Ntai I; Department of Chemistry, Proteomics Center of Excellence, Northwestern University, Evanston, IL 60208.
  • Fornelli L; Department of Molecular Biosciences, Proteomics Center of Excellence, Northwestern University, Evanston, IL 60208.
  • DeHart CJ; Department of Chemistry, Proteomics Center of Excellence, Northwestern University, Evanston, IL 60208.
  • Hutton JE; Department of Molecular Biosciences, Proteomics Center of Excellence, Northwestern University, Evanston, IL 60208.
  • Doubleday PF; Department of Chemistry, Proteomics Center of Excellence, Northwestern University, Evanston, IL 60208.
  • LeDuc RD; Department of Molecular Biosciences, Proteomics Center of Excellence, Northwestern University, Evanston, IL 60208.
  • van Nispen AJ; Department of Chemistry, Proteomics Center of Excellence, Northwestern University, Evanston, IL 60208.
  • Fellers RT; Department of Molecular Biosciences, Proteomics Center of Excellence, Northwestern University, Evanston, IL 60208.
  • Whiteley G; Department of Chemistry, Proteomics Center of Excellence, Northwestern University, Evanston, IL 60208.
  • Boja ES; Department of Molecular Biosciences, Proteomics Center of Excellence, Northwestern University, Evanston, IL 60208.
  • Rodriguez H; Department of Chemistry, Proteomics Center of Excellence, Northwestern University, Evanston, IL 60208.
  • Kelleher NL; Department of Molecular Biosciences, Proteomics Center of Excellence, Northwestern University, Evanston, IL 60208.
Proc Natl Acad Sci U S A ; 115(16): 4140-4145, 2018 04 17.
Article in En | MEDLINE | ID: mdl-29610327
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Colorectal Neoplasms / Protein Processing, Post-Translational / Proto-Oncogene Proteins p21(ras) / Point Mutation / Mutation, Missense / Neoplasm Proteins Limits: Humans Language: En Journal: Proc Natl Acad Sci U S A Year: 2018 Document type: Article
Fulltext
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Colorectal Neoplasms / Protein Processing, Post-Translational / Proto-Oncogene Proteins p21(ras) / Point Mutation / Mutation, Missense / Neoplasm Proteins Limits: Humans Language: En Journal: Proc Natl Acad Sci U S A Year: 2018 Document type: Article