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Maca polysaccharides: Extraction optimization, structural features and anti-fatigue activities.
Li, Yujuan; Xin, Yizhou; Xu, Fangxue; Zheng, Mengmeng; Xi, Xiaozhi; Cui, Xiaowei; Cao, Hui; Guo, Hong; Han, Chunchao.
Affiliation
  • Li Y; School of Pharmacy, Shandong University of Traditional Chinese Medicine, Jinan 250355, People's Republic of China.
  • Xin Y; The Afliated Hospital of Shandong University of Traditional Chinese Medicine, Jinan 250011, People's Republic of China.
  • Xu F; School of Pharmacy, Shandong University of Traditional Chinese Medicine, Jinan 250355, People's Republic of China.
  • Zheng M; School of Pharmacy, Shandong University of Traditional Chinese Medicine, Jinan 250355, People's Republic of China.
  • Xi X; School of Pharmacy, Shandong University of Traditional Chinese Medicine, Jinan 250355, People's Republic of China.
  • Cui X; School of Pharmacy, Shandong University of Traditional Chinese Medicine, Jinan 250355, People's Republic of China.
  • Cao H; School of Pharmacy, Shandong University of Traditional Chinese Medicine, Jinan 250355, People's Republic of China.
  • Guo H; School of Pharmacy, Shandong University of Traditional Chinese Medicine, Jinan 250355, People's Republic of China.
  • Han C; School of Pharmacy, Shandong University of Traditional Chinese Medicine, Jinan 250355, People's Republic of China. Electronic address: chunchaoh@126.com.
Int J Biol Macromol ; 115: 618-624, 2018 Aug.
Article in En | MEDLINE | ID: mdl-29665394
ABSTRACT
The maca polysaccharides optimal extraction conditions were obtained by using response surface methodology (RSM) method and the anti-fatigue activity of maca polysaccharides (MCP) was explored. The maca polysaccharides extract yield of RSM could reach 9.97 mg/g by using the model predicts, and the total sugar and protein purity were 61.00% and 4.46% with the further isolation process, respectively. And the monosaccharide compositions obtained by gas chromatograph (GC) were composed of rhamnose (rha), glucose (glc), galactose (gal) with the ratio of 2.3410.211.00. Furthermore, the anti-fatigue activity was evaluated by the swimming parameter, biochemistry parameters (liver glycogen (LG), blood urea nitrogen (BUN), and lactic acid (LD)), the result indicated that the low-dose maca polysaccharides group had the significant anti-fatigue activity.
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Polysaccharides / Lepidium / Fatigue Type of study: Prognostic_studies Limits: Animals Language: En Journal: Int J Biol Macromol Year: 2018 Document type: Article

Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Polysaccharides / Lepidium / Fatigue Type of study: Prognostic_studies Limits: Animals Language: En Journal: Int J Biol Macromol Year: 2018 Document type: Article