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An innovative appendage invagination procedure to reduce thrombus formation - a numerical model.
Hazan, Ori; Sternik, Leonid; Waiss, Dar; Eldar, Michael; Hoffer, Oshrit; Goitein, Orly; Kuperstein, Rafael; Konen, Eli; Ovadia-Blechman, Zehava.
Affiliation
  • Hazan O; a The Sackler Faculty of Medicine , Tel Aviv University , Ramat Aviv , Israel.
  • Sternik L; b School of Medical Engineering , Afeka -Tel Aviv Academic College of Engineering , Tel-Aviv , Israel.
  • Waiss D; c Leviev Heart Center, Chaim Sheba Medical Center , Tel Hashomer , Israel.
  • Eldar M; d Department of Biomedical Engineering, Faculty of Engineering , Tel Aviv University , Tel Aviv , Israel.
  • Hoffer O; a The Sackler Faculty of Medicine , Tel Aviv University , Ramat Aviv , Israel.
  • Goitein O; c Leviev Heart Center, Chaim Sheba Medical Center , Tel Hashomer , Israel.
  • Kuperstein R; e School of Electrical Engineering , Afeka -Tel Aviv Academic College of Engineering , Tel-Aviv , Israel.
  • Konen E; f Imaging Department , Sheba Medical Center , Tel-HaShomer , Israel.
  • Ovadia-Blechman Z; c Leviev Heart Center, Chaim Sheba Medical Center , Tel Hashomer , Israel.
Comput Methods Biomech Biomed Engin ; 21(4): 370-378, 2018 Mar.
Article in En | MEDLINE | ID: mdl-29722572
ABSTRACT
Invagination is an innovative technique for closing the left atrial appendage (LAA) to reduce the risk of thrombi formation. The influence of LAA invagination on the flow fields in the atria was investigated based on a computational fluid dynamics. The simulation results demonstrated that the novel invagination process can eliminate low velocities (blood stasis) and low shear rate and thus decrease the risk of thrombus formation during atrial fibrillation. This innovative technique may enhance the clinical treatment of patients with atrial fibrillation by improving the atrial flow field while lowering the risk of creating emboli.
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Thrombosis / Numerical Analysis, Computer-Assisted / Atrial Appendage Limits: Animals / Humans Language: En Journal: Comput Methods Biomech Biomed Engin Journal subject: ENGENHARIA BIOMEDICA / FISIOLOGIA Year: 2018 Document type: Article Affiliation country:
Fulltext
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Thrombosis / Numerical Analysis, Computer-Assisted / Atrial Appendage Limits: Animals / Humans Language: En Journal: Comput Methods Biomech Biomed Engin Journal subject: ENGENHARIA BIOMEDICA / FISIOLOGIA Year: 2018 Document type: Article Affiliation country: