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Flavones-bound in benzodiazepine site on GABAA receptor: Concomitant anxiolytic-like and cognitive-enhancing effects produced by Isovitexin and 6-C-glycoside-Diosmetin.
Oliveira, Daniela Rodrigues de; Todo, Andréia Hatsue; Rêgo, Gizelda Maia; Cerutti, Janete Maria; Cavalheiro, Alberto José; Rando, Daniela Gonçales Galasse; Cerutti, Suzete Maria.
Affiliation
  • Oliveira DR; Universidade Federal de São Paulo, Departamento de Patologia, São Paulo, SP, Brazil; Universidade Federal de São Paulo, Departamento de Ciências Biológicas, Laboratório de Farmacologia Celular e Comportamental, Diadema, SP, Brazil; Universidade Federal de São Paulo, Departamento de Morfologia e Gené
  • Todo AH; Medicinal Chemistry Research Group from the Federal University of São Paulo, Department of Pharmaceutical Sciences, Universidade Federal de Sao Paulo, Diadema, SP, Brazil.
  • Rêgo GM; Brazilian Agricultural Research Corporation (EMBRAPA), Department of Forestry Colombo, Paraná, Brazil.
  • Cerutti JM; Universidade Federal de São Paulo, Departamento de Morfologia e Genética, Laboratório Bases Genéticas do Tumor da Tiróide, São Paulo, SP, Brazil.
  • Cavalheiro AJ; Nuclei of Bioassay, Biosynthesis and Ecophysiology of Natural Products (NuBBE), Sao Paulo State University, UNESP, Araraquara, SP, Brazil.
  • Rando DGG; Medicinal Chemistry Research Group from the Federal University of São Paulo, Department of Pharmaceutical Sciences, Universidade Federal de Sao Paulo, Diadema, SP, Brazil.
  • Cerutti SM; Universidade Federal de São Paulo, Departamento de Ciências Biológicas, Laboratório de Farmacologia Celular e Comportamental, Diadema, SP, Brazil. Electronic address: smcerutti@unifesp.br.
Eur J Pharmacol ; 831: 77-86, 2018 Jul 15.
Article in En | MEDLINE | ID: mdl-29738701
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Anti-Anxiety Agents / Behavior, Animal / Flavonoids / Brain / Cognition / Receptors, GABA-A / Nootropic Agents / Apigenin / Diazepam Type of study: Prognostic_studies Limits: Animals Language: En Journal: Eur J Pharmacol Year: 2018 Document type: Article
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Anti-Anxiety Agents / Behavior, Animal / Flavonoids / Brain / Cognition / Receptors, GABA-A / Nootropic Agents / Apigenin / Diazepam Type of study: Prognostic_studies Limits: Animals Language: En Journal: Eur J Pharmacol Year: 2018 Document type: Article