Serum Copper is not Altered in Frontotemporal Lobar Degeneration.
J Alzheimers Dis
; 63(4): 1427-1432, 2018.
Article
in En
| MEDLINE
| ID: mdl-29843237
ABSTRACT
Meta-analyses show copper dyshomeostasis in Alzheimer's disease. However, a study evaluating copper changes in other neurodegenerative forms of dementia has not yet been performed. In this study, we assessed copper, ceruloplasmin, copper not bound to ceruloplasmin, and copper to ceruloplasmin ratio in 85 patients affected by frontotemporal lobar degeneration (FTLD) and 55 healthy controls. Data were analyzed through multivariate ANOVA models taking into account age and sex as covariates and the stratification for FTLD variants, after calculating power analysis to ensure the reliability of the conclusions drawn. The study revealed no difference between the groups.
Key words
Full text:
1
Collection:
01-internacional
Database:
MEDLINE
Main subject:
Copper
/
Frontotemporal Lobar Degeneration
Limits:
Aged
/
Female
/
Humans
/
Male
/
Middle aged
Language:
En
Journal:
J Alzheimers Dis
Journal subject:
GERIATRIA
/
NEUROLOGIA
Year:
2018
Document type:
Article
Affiliation country: