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Systematic evaluation of CRISPR-Cas systems reveals design principles for genome editing in human cells.
Wang, Yuanming; Liu, Kaiwen Ivy; Sutrisnoh, Norfala-Aliah Binte; Srinivasan, Harini; Zhang, Junyi; Li, Jia; Zhang, Fan; Lalith, Charles Richard John; Xing, Heyun; Shanmugam, Raghuvaran; Foo, Jia Nee; Yeo, Hwee Ting; Ooi, Kean Hean; Bleckwehl, Tore; Par, Yi Yun Rachel; Lee, Shi Mun; Ismail, Nur Nadiah Binte; Sanwari, Nur Aidah Binti; Lee, Si Ting Vanessa; Lew, Jan; Tan, Meng How.
Affiliation
  • Wang Y; School of Chemical and Biomedical Engineering, Nanyang Technological University, Singapore, 637459, Singapore.
  • Liu KI; Genome Institute of Singapore, Agency for Science Technology and Research, Singapore, 138672, Singapore.
  • Sutrisnoh NB; Genome Institute of Singapore, Agency for Science Technology and Research, Singapore, 138672, Singapore.
  • Srinivasan H; Genome Institute of Singapore, Agency for Science Technology and Research, Singapore, 138672, Singapore.
  • Zhang J; School of Biological Sciences, Nanyang Technological University, Singapore, 637551, Singapore.
  • Li J; School of Chemical and Biomedical Engineering, Nanyang Technological University, Singapore, 637459, Singapore.
  • Zhang F; Genome Institute of Singapore, Agency for Science Technology and Research, Singapore, 138672, Singapore.
  • Lalith CRJ; School of Chemical and Biomedical Engineering, Nanyang Technological University, Singapore, 637459, Singapore.
  • Xing H; Genome Institute of Singapore, Agency for Science Technology and Research, Singapore, 138672, Singapore.
  • Shanmugam R; School of Chemical and Biomedical Engineering, Nanyang Technological University, Singapore, 637459, Singapore.
  • Foo JN; Genome Institute of Singapore, Agency for Science Technology and Research, Singapore, 138672, Singapore.
  • Yeo HT; Genome Institute of Singapore, Agency for Science Technology and Research, Singapore, 138672, Singapore.
  • Ooi KH; Genome Institute of Singapore, Agency for Science Technology and Research, Singapore, 138672, Singapore.
  • Bleckwehl T; School of Chemical and Biomedical Engineering, Nanyang Technological University, Singapore, 637459, Singapore.
  • Par YYR; School of Chemical and Biomedical Engineering, Nanyang Technological University, Singapore, 637459, Singapore.
  • Lee SM; Genome Institute of Singapore, Agency for Science Technology and Research, Singapore, 138672, Singapore.
  • Ismail NNB; Genome Institute of Singapore, Agency for Science Technology and Research, Singapore, 138672, Singapore.
  • Sanwari NAB; Lee Kong Chian School of Medicine, Nanyang Technological University, Singapore, 636921, Singapore.
  • Lee STV; Genome Institute of Singapore, Agency for Science Technology and Research, Singapore, 138672, Singapore.
  • Lew J; School of Biological Sciences, Nanyang Technological University, Singapore, 637551, Singapore.
  • Tan MH; School of Chemical and Biomedical Engineering, Nanyang Technological University, Singapore, 637459, Singapore.
Genome Biol ; 19(1): 62, 2018 05 29.
Article in En | MEDLINE | ID: mdl-29843790

Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: CRISPR-Cas Systems / Gene Editing Limits: Humans Language: En Journal: Genome Biol Journal subject: BIOLOGIA MOLECULAR / GENETICA Year: 2018 Document type: Article Affiliation country: Country of publication:

Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: CRISPR-Cas Systems / Gene Editing Limits: Humans Language: En Journal: Genome Biol Journal subject: BIOLOGIA MOLECULAR / GENETICA Year: 2018 Document type: Article Affiliation country: Country of publication: