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Plasmablastic lymphoma in Malawi.
Zuze, Takondwa; Painschab, Matthew S; Seguin, Ryan; Kudowa, Evarista; Kaimila, Bongani; Kasonkanji, Edwards; Tomoka, Tamiwe; Dhungel, Bal Mukunda; Mulenga, Maurice; Chikasema, Maria; Tewete, Blessings; Ntangwanika, Asekanadziwa; Chiyoyola, Sarah; Chimzimu, Fred; Kampani, Coxcilly; Krysiak, Robert; Montgomery, Nathan D; Fedoriw, Yuri; Gopal, Satish.
Affiliation
  • Zuze T; UNC Project-Malawi, Private Bag, A-104 Lilongwe, Malawi.
  • Painschab MS; UNC Project-Malawi, Private Bag, A-104 Lilongwe, Malawi.
  • Seguin R; 2University of North Carolina, Chapel Hill, USA.
  • Kudowa E; UNC Project-Malawi, Private Bag, A-104 Lilongwe, Malawi.
  • Kaimila B; 2University of North Carolina, Chapel Hill, USA.
  • Kasonkanji E; UNC Project-Malawi, Private Bag, A-104 Lilongwe, Malawi.
  • Tomoka T; UNC Project-Malawi, Private Bag, A-104 Lilongwe, Malawi.
  • Dhungel BM; UNC Project-Malawi, Private Bag, A-104 Lilongwe, Malawi.
  • Mulenga M; UNC Project-Malawi, Private Bag, A-104 Lilongwe, Malawi.
  • Chikasema M; 3University of Malawi College of Medicine, Blantyre, Malawi.
  • Tewete B; UNC Project-Malawi, Private Bag, A-104 Lilongwe, Malawi.
  • Ntangwanika A; 2University of North Carolina, Chapel Hill, USA.
  • Chiyoyola S; 4Kamuzu Central Hospital, Lilongwe, Malawi.
  • Chimzimu F; UNC Project-Malawi, Private Bag, A-104 Lilongwe, Malawi.
  • Kampani C; UNC Project-Malawi, Private Bag, A-104 Lilongwe, Malawi.
  • Krysiak R; UNC Project-Malawi, Private Bag, A-104 Lilongwe, Malawi.
  • Montgomery ND; UNC Project-Malawi, Private Bag, A-104 Lilongwe, Malawi.
  • Fedoriw Y; UNC Project-Malawi, Private Bag, A-104 Lilongwe, Malawi.
  • Gopal S; UNC Project-Malawi, Private Bag, A-104 Lilongwe, Malawi.
Infect Agent Cancer ; 13: 22, 2018.
Article in En | MEDLINE | ID: mdl-29988350
ABSTRACT
Plasmablastic lymphoma (PBL) clinical descriptions are scarce from sub-Saharan Africa (SSA) where both HIV and EBV are highly endemic. We identified 12 patients with pathologically confirmed PBL from a prospective cohort in Lilongwe, Malawi. Median age was 46 (range 26-71), seven (58%) were male, and six (50%) were HIV-positive. Eight patients were treated with CHOP and four with a modified EPOCH regimen. One-year overall survival was 56% (95% CI 24-79%), without clear differences based on HIV status. PBL occurs in Malawi in HIV-positive and HIV-negative individuals and can be treated successfully with curative intent, even in a low-resource setting in SSA.
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Full text: 1 Collection: 01-internacional Database: MEDLINE Language: En Journal: Infect Agent Cancer Year: 2018 Document type: Article Affiliation country:
Fulltext
Add to My VHL
Print
XML
PubMed Links
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Full text: 1 Collection: 01-internacional Database: MEDLINE Language: En Journal: Infect Agent Cancer Year: 2018 Document type: Article Affiliation country: