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Reference Parameters for Protein Hydrogen Exchange Rates.
Nguyen, David; Mayne, Leland; Phillips, Michael C; Walter Englander, S.
Affiliation
  • Nguyen D; Johnson Research Foundation, Department of Biochemistry and Biophysics, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA. nguyend2@pennmedicine.upenn.edu.
  • Mayne L; Johnson Research Foundation, Department of Biochemistry and Biophysics, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA.
  • Phillips MC; Children's Hospital of Philadelphia, Philadelphia, PA, USA.
  • Walter Englander S; Johnson Research Foundation, Department of Biochemistry and Biophysics, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA.
J Am Soc Mass Spectrom ; 29(9): 1936-1939, 2018 09.
Article in En | MEDLINE | ID: mdl-30022340
ABSTRACT
The analysis of many hydrogen exchange (HX) experiments depends on knowledge of exchange rates expected for the unstructured protein under the same conditions. We present here some minor adjustments to previously calibrated values and a stringent test of their accuracy. Graphical Abstract ᅟ.
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Mass Spectrometry / Proteins / Deuterium Exchange Measurement / Deuterium Language: En Journal: J Am Soc Mass Spectrom Year: 2018 Document type: Article Affiliation country:
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Mass Spectrometry / Proteins / Deuterium Exchange Measurement / Deuterium Language: En Journal: J Am Soc Mass Spectrom Year: 2018 Document type: Article Affiliation country: