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Phase 1, single-dose escalating study of marzeptacog alfa (activated), a recombinant factor VIIa variant, in patients with severe hemophilia.
Gruppo, R A; Malan, D; Kapocsi, J; Nemes, L; Hay, C R M; Boggio, L; Chowdary, P; Tagariello, G; von Drygalski, A; Hua, F; Scaramozza, M; Arkin, S.
Affiliation
  • Gruppo RA; Comprehensive Hemophilia and Thrombosis Center, Cincinnati Children's Hospital Medical Center, Cincinnati, OH, USA.
  • Malan D; Phoenix Pharma Pty Ltd, Mount Croix, Port Elizabeth, South Africa.
  • Kapocsi J; Semmelweis University 1st Department of Medicine, Budapest, Hungary.
  • Nemes L; National Hemophilia Center and Hemostasis Department, Medical Center of the Hungarian Defense Forces, Budapest, Hungary.
  • Hay CRM; University Department of Haematology, Manchester Royal Infirmary, Manchester, UK.
  • Boggio L; Hemophilia and Thrombophilia Center, Rush University Medical Center, Chicago, IL, USA.
  • Chowdary P; KD Haemophilia and Thrombosis Centre, Royal Free Hospital, London, UK.
  • Tagariello G; Department of Medicine, Hemophilia Center, Castelfranco Veneto Hospital, Castelfranco, Italy.
  • von Drygalski A; University of California San Diego, San Diego, CA, USA.
  • Hua F; Applied BioMath, Concord, MA, USA.
  • Scaramozza M; Early Clinical Development, Pfizer Worldwide R&D, Pfizer Inc., Cambridge, MA, USA.
  • Arkin S; Rare Disease Research Unit, Pfizer Inc., Cambridge, MA, USA.
J Thromb Haemost ; 16(10): 1984-1993, 2018 10.
Article in En | MEDLINE | ID: mdl-30151972
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Coagulants / Factor VIIa / Hemophilia B / Hemophilia A Type of study: Clinical_trials / Diagnostic_studies Limits: Adolescent / Adult / Humans / Male / Middle aged Country/Region as subject: Africa / America do norte / Europa Language: En Journal: J Thromb Haemost Journal subject: HEMATOLOGIA Year: 2018 Document type: Article Affiliation country:
Fulltext
Add to My VHL
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Coagulants / Factor VIIa / Hemophilia B / Hemophilia A Type of study: Clinical_trials / Diagnostic_studies Limits: Adolescent / Adult / Humans / Male / Middle aged Country/Region as subject: Africa / America do norte / Europa Language: En Journal: J Thromb Haemost Journal subject: HEMATOLOGIA Year: 2018 Document type: Article Affiliation country: