Relationship between inflammatory parameters and cardiovascular and lifestyle factors in the Mugello study oldest old.
Biomark Med
; 12(10): 1115-1124, 2018 10.
Article
in En
| MEDLINE
| ID: mdl-30203672
ABSTRACT
AIM:
To explore possible inter-relationships of various biomarkers of inflammation and lifestyle and other cardiovascular risk factors (age, gender, smoking history, hypertension, Type 2 diabetes, dyslipidemia, alteration of circadian rhythms, body mass index, calf circumference, thigh circumference, abdominal circumference) in the Mugello study oldest old.METHODS:
In 399 noninstitutionalized nonagenarians (291 women), whole blood cells, mean platelet volume, C-reactive protein, uric acid, gamma-glutamyl transferase were assessed.RESULTS:
Aging resulted as the only independent determinant for uric acid (<0.05), and abdominal circumference for C-reactive protein. Female gender (<0.01), and thigh circumference (<0.05) remained as determinants for mean platelet volume, age (<0.01), and male gender (<0.01) for gamma-glutamyl transferase, and Type 2 diabetes (≤0.01) and alteration of circadian rhythms (<0.05) for whole blood cells.CONCLUSION:
Several inflammatory parameters remain associated with adverse lifestyle and cardiovascular risk factors even among nonagenarians.Key words
Full text:
1
Collection:
01-internacional
Database:
MEDLINE
Main subject:
Biomarkers
/
Cardiovascular Diseases
/
Life Style
Type of study:
Etiology_studies
/
Risk_factors_studies
Limits:
Aged80
/
Female
/
Humans
/
Male
Language:
En
Journal:
Biomark Med
Journal subject:
BIOQUIMICA
/
MEDICINA
Year:
2018
Document type:
Article
Affiliation country: