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Identification of multiple risk loci and regulatory mechanisms influencing susceptibility to multiple myeloma.
Went, Molly; Sud, Amit; Försti, Asta; Halvarsson, Britt-Marie; Weinhold, Niels; Kimber, Scott; van Duin, Mark; Thorleifsson, Gudmar; Holroyd, Amy; Johnson, David C; Li, Ni; Orlando, Giulia; Law, Philip J; Ali, Mina; Chen, Bowang; Mitchell, Jonathan S; Gudbjartsson, Daniel F; Kuiper, Rowan; Stephens, Owen W; Bertsch, Uta; Broderick, Peter; Campo, Chiara; Bandapalli, Obul R; Einsele, Hermann; Gregory, Walter A; Gullberg, Urban; Hillengass, Jens; Hoffmann, Per; Jackson, Graham H; Jöckel, Karl-Heinz; Johnsson, Ellinor; Kristinsson, Sigurður Y; Mellqvist, Ulf-Henrik; Nahi, Hareth; Easton, Douglas; Pharoah, Paul; Dunning, Alison; Peto, Julian; Canzian, Federico; Swerdlow, Anthony; Eeles, Rosalind A; Kote-Jarai, ZSofia; Muir, Kenneth; Pashayan, Nora; Nickel, Jolanta; Nöthen, Markus M; Rafnar, Thorunn; Ross, Fiona M; da Silva Filho, Miguel Inacio; Thomsen, Hauke.
Affiliation
  • Went M; Division of Genetics and Epidemiology, The Institute of Cancer Research, London, SW7 3RP, UK.
  • Sud A; Division of Genetics and Epidemiology, The Institute of Cancer Research, London, SW7 3RP, UK.
  • Försti A; German Cancer Research Center, 69120, Heidelberg, Germany.
  • Halvarsson BM; Center for Primary Health Care Research, Lund University, SE-205 02, Malmo, Sweden.
  • Weinhold N; Hematology and Transfusion Medicine, Department of Laboratory Medicine, BMC B13, Lund University, SE-221 84, Lund, Sweden.
  • Kimber S; Myeloma Institute for Research and Therapy, University of Arkansas for Medical Sciences, Little Rock, AR, 72205, USA.
  • van Duin M; Department of Internal Medicine V, University of Heidelberg, 69117, Heidelberg, Germany.
  • Thorleifsson G; Division of Molecular Pathology, The Institute of Cancer Research, London, SW7 3RP, UK.
  • Holroyd A; Department of Hematology, Erasmus MC Cancer Institute, 3075 EA, Rotterdam, The Netherlands.
  • Johnson DC; deCODE Genetics, Sturlugata 8, IS-101, Reykjavik, Iceland.
  • Li N; Division of Genetics and Epidemiology, The Institute of Cancer Research, London, SW7 3RP, UK.
  • Orlando G; Division of Molecular Pathology, The Institute of Cancer Research, London, SW7 3RP, UK.
  • Law PJ; Division of Genetics and Epidemiology, The Institute of Cancer Research, London, SW7 3RP, UK.
  • Ali M; Division of Genetics and Epidemiology, The Institute of Cancer Research, London, SW7 3RP, UK.
  • Chen B; Division of Genetics and Epidemiology, The Institute of Cancer Research, London, SW7 3RP, UK.
  • Mitchell JS; Hematology and Transfusion Medicine, Department of Laboratory Medicine, BMC B13, Lund University, SE-221 84, Lund, Sweden.
  • Gudbjartsson DF; German Cancer Research Center, 69120, Heidelberg, Germany.
  • Kuiper R; Division of Genetics and Epidemiology, The Institute of Cancer Research, London, SW7 3RP, UK.
  • Stephens OW; deCODE Genetics, Sturlugata 8, IS-101, Reykjavik, Iceland.
  • Bertsch U; School of Engineering and Natural Sciences, University of Iceland, IS-101, Reykjavik, Iceland.
  • Broderick P; Department of Hematology, Erasmus MC Cancer Institute, 3075 EA, Rotterdam, The Netherlands.
  • Campo C; Myeloma Institute for Research and Therapy, University of Arkansas for Medical Sciences, Little Rock, AR, 72205, USA.
  • Bandapalli OR; German Cancer Research Center, 69120, Heidelberg, Germany.
  • Einsele H; National Centre of Tumor Diseases, 69120, Heidelberg, Germany.
  • Gregory WA; Division of Genetics and Epidemiology, The Institute of Cancer Research, London, SW7 3RP, UK.
  • Gullberg U; German Cancer Research Center, 69120, Heidelberg, Germany.
  • Hillengass J; German Cancer Research Center, 69120, Heidelberg, Germany.
  • Hoffmann P; University Clinic of Würzburg, 97080, Würzburg, Germany.
  • Jackson GH; Clinical Trials Research Unit, University of Leeds, Leeds, LS2 9PH, UK.
  • Jöckel KH; Hematology and Transfusion Medicine, Department of Laboratory Medicine, BMC B13, Lund University, SE-221 84, Lund, Sweden.
  • Johnsson E; Department of Internal Medicine V, University of Heidelberg, 69117, Heidelberg, Germany.
  • Kristinsson SY; Institute of Human Genetics, University of Bonn, D-53127, Bonn, Germany.
  • Mellqvist UH; Division of Medical Genetics, Department of Biomedicine, University of Basel, 4003, Basel, Switzerland.
  • Nahi H; Royal Victoria Infirmary, Newcastle upon Tyne, NE1 4LP, UK.
  • Easton D; Institute for Medical Informatics, Biometry and Epidemiology, University Hospital Essen, University of Duisburg-Essen, Essen, D-45147, Germany.
  • Pharoah P; Hematology and Transfusion Medicine, Department of Laboratory Medicine, BMC B13, Lund University, SE-221 84, Lund, Sweden.
  • Dunning A; Department of Hematology, Landspitali, National University Hospital of Iceland, IS-101, Reykjavik, Iceland.
  • Peto J; Section of Hematology, Sahlgrenska University Hospital, Gothenburg, 413 45, Sweden.
  • Canzian F; Center for Hematology and Regenerative Medicine, SE-171 77, Stockholm, Sweden.
  • Swerdlow A; Centre for Cancer Genetic Epidemiology, Department of Oncology, University of Cambridge, Cambridge, CB1 8RN, UK.
  • Eeles RA; Centre for Cancer Genetic Epidemiology, Department of Public Health and Primary Care, University of Cambridge, Cambridge, CB1 8RN, UK.
  • Kote-Jarai Z; Centre for Cancer Genetic Epidemiology, Department of Oncology, University of Cambridge, Cambridge, CB1 8RN, UK.
  • Muir K; Centre for Cancer Genetic Epidemiology, Department of Public Health and Primary Care, University of Cambridge, Cambridge, CB1 8RN, UK.
  • Pashayan N; Centre for Cancer Genetic Epidemiology, Department of Oncology, University of Cambridge, Cambridge, CB1 8RN, UK.
  • Nickel J; Department of Non-Communicable Disease Epidemiology, London School of Hygiene and Tropical Medicine, London, WC1E 7HT, UK.
  • Nöthen MM; Genomic Epidemiology Group, German Cancer Research Center (DKFZ), Heidelberg, 69120, Germany.
  • Rafnar T; Division of Genetics and Epidemiology, The Institute of Cancer Research, London, SW7 3RP, UK.
  • Ross FM; Division of Breast Cancer Research, The Institute of Cancer Research, London, SW7 3RP, UK.
  • da Silva Filho MI; Division of Genetics and Epidemiology, The Institute of Cancer Research, London, SW7 3RP, UK.
  • Thomsen H; Royal Marsden NHS Foundation Trust, Fulham Road, London, SW3 6JJ, UK.
Nat Commun ; 9(1): 3707, 2018 09 13.
Article in En | MEDLINE | ID: mdl-30213928
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Genetic Predisposition to Disease / Polymorphism, Single Nucleotide / Multiple Myeloma Type of study: Diagnostic_studies / Etiology_studies / Prognostic_studies / Risk_factors_studies / Systematic_reviews Limits: Female / Humans / Male Language: En Journal: Nat Commun Journal subject: BIOLOGIA / CIENCIA Year: 2018 Document type: Article Affiliation country:
Fulltext
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Genetic Predisposition to Disease / Polymorphism, Single Nucleotide / Multiple Myeloma Type of study: Diagnostic_studies / Etiology_studies / Prognostic_studies / Risk_factors_studies / Systematic_reviews Limits: Female / Humans / Male Language: En Journal: Nat Commun Journal subject: BIOLOGIA / CIENCIA Year: 2018 Document type: Article Affiliation country: