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Imatinib stimulates prostaglandin E2 and attenuates cytokine release via EP4 receptor activation.
Bärnthaler, Thomas; Jandl, Katharina; Sill, Heinz; Uhl, Barbara; Schreiber, Yannick; Grill, Magdalena; Thomas, Dominique; Schicho, Rudolf; Marsche, Gunther; Frank, Sasa; Heinemann, Akos; Schuligoi, Rufina.
Affiliation
  • Bärnthaler T; Division of Pharmacology, Otto Loewi Research Center, Medical University of Graz, Graz, Austria.
  • Jandl K; Ludwig Boltzmann Institute Lung Vascular Research, Graz, Austria.
  • Sill H; Division of Hematology, Department of Internal Medicine, Medical University of Graz, Graz, Austria.
  • Uhl B; Division of Hematology, Department of Internal Medicine, Medical University of Graz, Graz, Austria.
  • Schreiber Y; Fraunhofer Institute for Molecular Biology and Applied Ecology IME, Project Group TMP, Frankfurt, Germany.
  • Grill M; Division of Pharmacology, Otto Loewi Research Center, Medical University of Graz, Graz, Austria.
  • Thomas D; Pharmazentrum Frankfurt/ZAFES Institute of Clinical Pharmacology, Goethe-University Frankfurt, Frankfurt, Germany.
  • Schicho R; Division of Pharmacology, Otto Loewi Research Center, Medical University of Graz, Graz, Austria; BioTechMed, Graz, Austria.
  • Marsche G; Division of Pharmacology, Otto Loewi Research Center, Medical University of Graz, Graz, Austria; BioTechMed, Graz, Austria.
  • Frank S; Division of Molecular Biology and Biochemisty, Gottfried Schatz Research Center, Medical University of Graz, Graz, Austria.
  • Heinemann A; Division of Pharmacology, Otto Loewi Research Center, Medical University of Graz, Graz, Austria; BioTechMed, Graz, Austria.
  • Schuligoi R; Division of Pharmacology, Otto Loewi Research Center, Medical University of Graz, Graz, Austria. Electronic address: rufina.schuligoi@medunigraz.at.
J Allergy Clin Immunol ; 143(2): 794-797.e10, 2019 02.
Article in En | MEDLINE | ID: mdl-30336225
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Abelson murine leukemia virus / Monocytes / Dinoprostone / Leukemia / Proto-Oncogene Proteins c-bcr / Receptors, Prostaglandin E, EP4 Subtype / Imatinib Mesylate Limits: Humans Language: En Journal: J Allergy Clin Immunol Year: 2019 Document type: Article Affiliation country:
Fulltext
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Abelson murine leukemia virus / Monocytes / Dinoprostone / Leukemia / Proto-Oncogene Proteins c-bcr / Receptors, Prostaglandin E, EP4 Subtype / Imatinib Mesylate Limits: Humans Language: En Journal: J Allergy Clin Immunol Year: 2019 Document type: Article Affiliation country: