Spontaneous and induced interferon production by peripheral blood leucocytes from control population and patients with herpes genitalis.
J Med Virol
; 22(1): 25-34, 1987 May.
Article
in En
| MEDLINE
| ID: mdl-3035077
ABSTRACT
The spontaneous and PHA induced levels of interferon were measured in peripheral blood leucocyte cultures of twenty-eight individuals diagnosed as positive for herpes genitalis, and in a group of control subjects. As reported by Cunningham and Merigan [1983] for herpes labialis, leucocytes from individuals with herpes genitalis produced low levels of interferon spontaneously; however, similar results were found for individuals within the control population. No statistically significant difference could be found for PHA induced interferon levels, antigen induced interferon levels, or helper/suppressor cell ratios between the herpes genitalis population and control population. Our results indicate that interferon does not play a major role in the latency or recurrence of herpes genitalis.
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Collection:
01-internacional
Database:
MEDLINE
Main subject:
Herpes Genitalis
/
Interferon Type I
/
Interferon-gamma
/
Leukocytes
Limits:
Humans
Language:
En
Journal:
J Med Virol
Year:
1987
Document type:
Article