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Pharmacological Inhibition of Serine Palmitoyl Transferase and Sphingosine Kinase-1/-2 Inhibits Merkel Cell Carcinoma Cell Proliferation.
Bhat, Vishwanath Kumble; Bernhart, Eva; Plastira, Ioanna; Fan, Kaiji; Ghaffari-Tabrizi-Wizsy, Nassim; Wadsack, Christian; Rechberger, Gerald; Eichmann, Thomas; Asslaber, Martin; Spassova, Ivelina; Verhaegen, Monique E; Malle, Ernst; Becker, Jürgen C; Sattler, Wolfgang.
Affiliation
  • Bhat VK; Gottfried Schatz Research Center, Division of Molecular Biology and Biochemistry, Medical University of Graz, Graz, Austria.
  • Bernhart E; Gottfried Schatz Research Center, Division of Molecular Biology and Biochemistry, Medical University of Graz, Graz, Austria.
  • Plastira I; Gottfried Schatz Research Center, Division of Molecular Biology and Biochemistry, Medical University of Graz, Graz, Austria.
  • Fan K; Department of Dermatology and Venereology, Medical University of Graz, Graz, Austria; Department of Translational Skin Cancer Research, University Hospital Essen, Essen, Germany.
  • Ghaffari-Tabrizi-Wizsy N; Otto Loewi Research Center, Division of Immunology and Pathophysiology, Medical University of Graz, Graz, Austria.
  • Wadsack C; Department of Obstetrics and Gynecology, Medical University of Graz, Graz, Austria.
  • Rechberger G; Institute of Molecular Biosciences, University of Graz, Graz, Austria; Center for Explorative Lipidomics, BioTechMed-Graz, Graz, Austria.
  • Eichmann T; Institute of Molecular Biosciences, University of Graz, Graz, Austria; Center for Explorative Lipidomics, BioTechMed-Graz, Graz, Austria.
  • Asslaber M; Diagnostic and Research Center for Molecular Biomedicine, Institute of Pathology, Medical University of Graz, Graz, Austria.
  • Spassova I; Department of Translational Skin Cancer Research, University Hospital Essen, Essen, Germany.
  • Verhaegen ME; Department of Dermatology, University of Michigan, Ann Arbor, Michigan, USA.
  • Malle E; Gottfried Schatz Research Center, Division of Molecular Biology and Biochemistry, Medical University of Graz, Graz, Austria.
  • Becker JC; Department of Translational Skin Cancer Research, University Hospital Essen, Essen, Germany; German Cancer Consortium (DKTK/DKFZ), Heidelberg, Germany. Electronic address: j.becker@dkfz.de.
  • Sattler W; Gottfried Schatz Research Center, Division of Molecular Biology and Biochemistry, Medical University of Graz, Graz, Austria; Center for Explorative Lipidomics, BioTechMed-Graz, Graz, Austria. Electronic address: wolfgang.sattler@medunigraz.at.
J Invest Dermatol ; 139(4): 807-817, 2019 04.
Article in En | MEDLINE | ID: mdl-30399362
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Skin Neoplasms / Tumor Virus Infections / Fatty Acids, Monounsaturated / Carcinoma, Merkel Cell / Phosphotransferases (Alcohol Group Acceptor) / Polyomavirus Infections / Serine C-Palmitoyltransferase Limits: Humans Language: En Journal: J Invest Dermatol Year: 2019 Document type: Article Affiliation country:
Fulltext
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Skin Neoplasms / Tumor Virus Infections / Fatty Acids, Monounsaturated / Carcinoma, Merkel Cell / Phosphotransferases (Alcohol Group Acceptor) / Polyomavirus Infections / Serine C-Palmitoyltransferase Limits: Humans Language: En Journal: J Invest Dermatol Year: 2019 Document type: Article Affiliation country: