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Learnings about the complexity of extracellular tau aid development of a blood-based screen for Alzheimer's disease.
Chen, Zhicheng; Mengel, David; Keshavan, Ashvini; Rissman, Robert A; Billinton, Andrew; Perkinton, Michael; Percival-Alwyn, Jennifer; Schultz, Aaron; Properzi, Michael; Johnson, Keith; Selkoe, Dennis J; Sperling, Reisa A; Patel, Purvish; Zetterberg, Henrik; Galasko, Douglas; Schott, Jonathan M; Walsh, Dominic M.
Affiliation
  • Chen Z; Laboratory for Neurodegenerative Research, Ann Romney Center for Neurologic Diseases, Brigham and Women's Hospital and Harvard Medical School, Boston, MA, USA.
  • Mengel D; Laboratory for Neurodegenerative Research, Ann Romney Center for Neurologic Diseases, Brigham and Women's Hospital and Harvard Medical School, Boston, MA, USA.
  • Keshavan A; Department of Neurodegenerative Disease, UCL Institute of Neurology, Queen Square, London, England.
  • Rissman RA; Department of Neurosciences, University of California San Diego, La Jolla, CA, USA; VA San Diego Healthcare System, La Jolla, CA, USA.
  • Billinton A; AstraZeneca Neuroscience Innovative Medicines, MedImmune Ltd, Cambridge, England.
  • Perkinton M; AstraZeneca Neuroscience Innovative Medicines, MedImmune Ltd, Cambridge, England.
  • Percival-Alwyn J; AstraZeneca Neuroscience Innovative Medicines, MedImmune Ltd, Cambridge, England.
  • Schultz A; Massachusetts General Hospital and Harvard Medical School, Charlestown, MA, USA.
  • Properzi M; Massachusetts General Hospital and Harvard Medical School, Charlestown, MA, USA.
  • Johnson K; Massachusetts General Hospital and Harvard Medical School, Charlestown, MA, USA.
  • Selkoe DJ; Laboratory for Neurodegenerative Research, Ann Romney Center for Neurologic Diseases, Brigham and Women's Hospital and Harvard Medical School, Boston, MA, USA.
  • Sperling RA; Laboratory for Neurodegenerative Research, Ann Romney Center for Neurologic Diseases, Brigham and Women's Hospital and Harvard Medical School, Boston, MA, USA.
  • Patel P; Quanterix Corporation, Lexington, MA, USA.
  • Zetterberg H; Department of Neurodegenerative Disease, UCL Institute of Neurology, Queen Square, London, England; UK Dementia Research Institute at UCL, London, England; Clinical Neurochemistry Laboratory, Sahlgrenska University Hospital, Mölndal, Sweden; Department of Psychiatry and Neurochemistry, Institute of
  • Galasko D; Department of Neurosciences, University of California San Diego, La Jolla, CA, USA.
  • Schott JM; Department of Neurodegenerative Disease, UCL Institute of Neurology, Queen Square, London, England.
  • Walsh DM; Laboratory for Neurodegenerative Research, Ann Romney Center for Neurologic Diseases, Brigham and Women's Hospital and Harvard Medical School, Boston, MA, USA; Department of Neurodegenerative Disease, UCL Institute of Neurology, Queen Square, London, England. Electronic address: dwalsh3@bwh.harvard.
Alzheimers Dement ; 15(3): 487-496, 2019 03.
Article in En | MEDLINE | ID: mdl-30419228
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Immunoassay / Tau Proteins / Alzheimer Disease / Cognitive Dysfunction Type of study: Diagnostic_studies / Etiology_studies / Incidence_studies / Observational_studies / Prognostic_studies / Risk_factors_studies Limits: Aged / Female / Humans / Male / Middle aged Language: En Journal: Alzheimers Dement Year: 2019 Document type: Article Affiliation country:
Fulltext
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Immunoassay / Tau Proteins / Alzheimer Disease / Cognitive Dysfunction Type of study: Diagnostic_studies / Etiology_studies / Incidence_studies / Observational_studies / Prognostic_studies / Risk_factors_studies Limits: Aged / Female / Humans / Male / Middle aged Language: En Journal: Alzheimers Dement Year: 2019 Document type: Article Affiliation country: