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Chromosomal translocation-mediated evasion from miRNA induces strong MEF2D fusion protein expression, causing inhibition of PAX5 transcriptional activity.
Hirano, Daiki; Hayakawa, Fumihiko; Yasuda, Takahiko; Tange, Naoyuki; Yamamoto, Hideyuki; Kojima, Yuki; Morishita, Takanobu; Imoto, Naoto; Tsuzuki, Shinobu; Mano, Hiroyuki; Naoe, Tomoki; Kiyoi, Hitoshi.
Affiliation
  • Hirano D; Department of Hematology and Oncology, Nagoya University Graduate School of Medicine, Nagoya, Japan.
  • Hayakawa F; Department of Hematology and Oncology, Nagoya University Graduate School of Medicine, Nagoya, Japan. bun-hy@med.nagoya-u.ac.jp.
  • Yasuda T; Department of Pathophysiological Laboratory Sciences, Nagoya University Graduate School of Medicine, Nagoya, Japan. bun-hy@med.nagoya-u.ac.jp.
  • Tange N; Clinical Research Center, Nagoya Medical Center, National Hospital Organization, Nagoya, Japan.
  • Yamamoto H; Department of Hematology and Oncology, Nagoya University Graduate School of Medicine, Nagoya, Japan.
  • Kojima Y; Department of Hematology and Oncology, Nagoya University Graduate School of Medicine, Nagoya, Japan.
  • Morishita T; Department of Hematology and Oncology, Nagoya University Graduate School of Medicine, Nagoya, Japan.
  • Imoto N; Department of Hematology and Oncology, Nagoya University Graduate School of Medicine, Nagoya, Japan.
  • Tsuzuki S; Department of Hematology, Ogaki Municipal Hospital, Ogaki, Japan.
  • Mano H; Department of Biochemistry, Aichi Medical University, School of Medicine, Nagakute, Japan.
  • Naoe T; Department of Cellular Signaling, Graduate School of Medicine, The University of Tokyo, Tokyo, Japan.
  • Kiyoi H; Nagoya Medical Center, Nagoya, Japan.
Oncogene ; 38(13): 2263-2274, 2019 03.
Article in En | MEDLINE | ID: mdl-30478446
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Translocation, Genetic / Oncogene Proteins, Fusion / MicroRNAs / PAX5 Transcription Factor / Precursor Cell Lymphoblastic Leukemia-Lymphoma Type of study: Prognostic_studies Limits: Humans Language: En Journal: Oncogene Journal subject: BIOLOGIA MOLECULAR / NEOPLASIAS Year: 2019 Document type: Article Affiliation country: Country of publication:
Fulltext
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Translocation, Genetic / Oncogene Proteins, Fusion / MicroRNAs / PAX5 Transcription Factor / Precursor Cell Lymphoblastic Leukemia-Lymphoma Type of study: Prognostic_studies Limits: Humans Language: En Journal: Oncogene Journal subject: BIOLOGIA MOLECULAR / NEOPLASIAS Year: 2019 Document type: Article Affiliation country: Country of publication: