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Acquisition of the Recurrent Gly101Val Mutation in BCL2 Confers Resistance to Venetoclax in Patients with Progressive Chronic Lymphocytic Leukemia.
Blombery, Piers; Anderson, Mary Ann; Gong, Jia-Nan; Thijssen, Rachel; Birkinshaw, Richard W; Thompson, Ella R; Teh, Charis E; Nguyen, Tamia; Xu, Zhen; Flensburg, Christoffer; Lew, Thomas E; Majewski, Ian J; Gray, Daniel H D; Westerman, David A; Tam, Constantine S; Seymour, John F; Czabotar, Peter E; Huang, David C S; Roberts, Andrew W.
Affiliation
  • Blombery P; Department of Pathology, Peter MacCallum Cancer Centre, Melbourne, Victoria, Australia. Piers.Blombery@petermac.org roberts@wehi.edu.au.
  • Anderson MA; Clinical Haematology, Peter MacCallum Cancer Centre and Royal Melbourne Hospital, Melbourne, Victoria, Australia.
  • Gong JN; Sir Peter MacCallum Department of Oncology, University of Melbourne, Melbourne, Victoria, Australia.
  • Thijssen R; Clinical Haematology, Peter MacCallum Cancer Centre and Royal Melbourne Hospital, Melbourne, Victoria, Australia.
  • Birkinshaw RW; The Walter and Eliza Hall Institute of Medical Research, Parkville, Victoria, Australia.
  • Thompson ER; Department of Medical Biology, University of Melbourne, Melbourne, Victoria, Australia.
  • Teh CE; The Walter and Eliza Hall Institute of Medical Research, Parkville, Victoria, Australia.
  • Nguyen T; Department of Medical Biology, University of Melbourne, Melbourne, Victoria, Australia.
  • Xu Z; The Walter and Eliza Hall Institute of Medical Research, Parkville, Victoria, Australia.
  • Flensburg C; Department of Medical Biology, University of Melbourne, Melbourne, Victoria, Australia.
  • Lew TE; The Walter and Eliza Hall Institute of Medical Research, Parkville, Victoria, Australia.
  • Majewski IJ; Department of Medical Biology, University of Melbourne, Melbourne, Victoria, Australia.
  • Gray DHD; Department of Pathology, Peter MacCallum Cancer Centre, Melbourne, Victoria, Australia.
  • Westerman DA; Sir Peter MacCallum Department of Oncology, University of Melbourne, Melbourne, Victoria, Australia.
  • Tam CS; The Walter and Eliza Hall Institute of Medical Research, Parkville, Victoria, Australia.
  • Seymour JF; Department of Medical Biology, University of Melbourne, Melbourne, Victoria, Australia.
  • Czabotar PE; Department of Pathology, Peter MacCallum Cancer Centre, Melbourne, Victoria, Australia.
  • Huang DCS; Sir Peter MacCallum Department of Oncology, University of Melbourne, Melbourne, Victoria, Australia.
  • Roberts AW; The Walter and Eliza Hall Institute of Medical Research, Parkville, Victoria, Australia.
Cancer Discov ; 9(3): 342-353, 2019 03.
Article in En | MEDLINE | ID: mdl-30514704
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Sulfonamides / Leukemia, Lymphocytic, Chronic, B-Cell / Bridged Bicyclo Compounds, Heterocyclic / Proto-Oncogene Proteins c-bcl-2 / Mutation Limits: Humans Language: En Journal: Cancer Discov Year: 2019 Document type: Article Country of publication:
Fulltext
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Sulfonamides / Leukemia, Lymphocytic, Chronic, B-Cell / Bridged Bicyclo Compounds, Heterocyclic / Proto-Oncogene Proteins c-bcl-2 / Mutation Limits: Humans Language: En Journal: Cancer Discov Year: 2019 Document type: Article Country of publication: