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Insulin-like growth factor-1 activates AMPK to augment mitochondrial function and correct neuronal metabolism in sensory neurons in type 1 diabetes.
Aghanoori, Mohamad-Reza; Smith, Darrell R; Shariati-Ievari, Shiva; Ajisebutu, Andrew; Nguyen, Annee; Desmond, Fiona; Jesus, Carlos H A; Zhou, Xiajun; Calcutt, Nigel A; Aliani, Michel; Fernyhough, Paul.
Affiliation
  • Aghanoori MR; Division of Neurodegenerative Disorders, St Boniface Hospital Albrechtsen Research Centre, Winnipeg, MB, Canada; Department of Pharmacology and Therapeutics, University of Manitoba, Winnipeg, MB, Canada.
  • Smith DR; Division of Neurodegenerative Disorders, St Boniface Hospital Albrechtsen Research Centre, Winnipeg, MB, Canada.
  • Shariati-Ievari S; Canadian Centre for Agri-Food Research in Health and Medicine, St. Boniface Hospital Albrechtsen Research Centre, Winnipeg, Canada.
  • Ajisebutu A; Division of Neurodegenerative Disorders, St Boniface Hospital Albrechtsen Research Centre, Winnipeg, MB, Canada.
  • Nguyen A; Department of Pathology, University of California San Diego, La Jolla, CA, USA.
  • Desmond F; Department of Pathology, University of California San Diego, La Jolla, CA, USA.
  • Jesus CHA; Department of Pathology, University of California San Diego, La Jolla, CA, USA.
  • Zhou X; Department of Pathology, University of California San Diego, La Jolla, CA, USA.
  • Calcutt NA; Department of Pathology, University of California San Diego, La Jolla, CA, USA.
  • Aliani M; Department of Human Nutritional Sciences, University of Manitoba, Winnipeg, MB, Canada; Canadian Centre for Agri-Food Research in Health and Medicine, St. Boniface Hospital Albrechtsen Research Centre, Winnipeg, Canada; Department of Physiology and Pathophysiology, University of Manitoba, Winnipeg,
  • Fernyhough P; Division of Neurodegenerative Disorders, St Boniface Hospital Albrechtsen Research Centre, Winnipeg, MB, Canada; Department of Pharmacology and Therapeutics, University of Manitoba, Winnipeg, MB, Canada. Electronic address: pfernyhough@sbrc.ca.
Mol Metab ; 20: 149-165, 2019 02.
Article in En | MEDLINE | ID: mdl-30545741
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Protein Kinases / Sensory Receptor Cells / Insulin-Like Growth Factor I / Diabetes Mellitus, Type 1 / Diabetic Neuropathies / Mitochondria Type of study: Etiology_studies / Prognostic_studies Limits: Animals Language: En Journal: Mol Metab Year: 2019 Document type: Article Affiliation country: Country of publication:
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Protein Kinases / Sensory Receptor Cells / Insulin-Like Growth Factor I / Diabetes Mellitus, Type 1 / Diabetic Neuropathies / Mitochondria Type of study: Etiology_studies / Prognostic_studies Limits: Animals Language: En Journal: Mol Metab Year: 2019 Document type: Article Affiliation country: Country of publication: