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Crystal structures of the human neurokinin 1 receptor in complex with clinically used antagonists.
Schöppe, Jendrik; Ehrenmann, Janosch; Klenk, Christoph; Rucktooa, Prakash; Schütz, Marco; Doré, Andrew S; Plückthun, Andreas.
Affiliation
  • Schöppe J; Department of Biochemistry, University of Zürich, Winterthurerstrasse 190, CH-8057, Zürich, Switzerland.
  • Ehrenmann J; Department of Biochemistry, University of Zürich, Winterthurerstrasse 190, CH-8057, Zürich, Switzerland.
  • Klenk C; Department of Biochemistry, University of Zürich, Winterthurerstrasse 190, CH-8057, Zürich, Switzerland.
  • Rucktooa P; Sosei Heptares, Steinmetz Building, Granta Park, Great Abington, Cambridge, CB21 6DG, UK.
  • Schütz M; Department of Biochemistry, University of Zürich, Winterthurerstrasse 190, CH-8057, Zürich, Switzerland.
  • Doré AS; Heptares Therapeutics Zürich AG, Grabenstrasse 11a, 8952, Zürich, Switzerland.
  • Plückthun A; Sosei Heptares, Steinmetz Building, Granta Park, Great Abington, Cambridge, CB21 6DG, UK.
Nat Commun ; 10(1): 17, 2019 01 03.
Article in En | MEDLINE | ID: mdl-30604743
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Receptors, Neurokinin-1 / Neurokinin-1 Receptor Antagonists Limits: Humans Language: En Journal: Nat Commun Journal subject: BIOLOGIA / CIENCIA Year: 2019 Document type: Article Affiliation country:
Fulltext
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Receptors, Neurokinin-1 / Neurokinin-1 Receptor Antagonists Limits: Humans Language: En Journal: Nat Commun Journal subject: BIOLOGIA / CIENCIA Year: 2019 Document type: Article Affiliation country: