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Oxidative Insults and Mitochondrial DNA Mutation Promote Enhanced Autophagy and Mitophagy Compromising Cell Viability in Pluripotent Cell Model of Mitochondrial Disease.
Lin, Dar-Shong; Huang, Yu-Wen; Ho, Che-Sheng; Hung, Pi-Lien; Hsu, Mei-Hsin; Wang, Tuan-Jen; Wu, Tsu-Yen; Lee, Tsung-Han; Huang, Zo-Darr; Chang, Po-Chun; Chiang, Ming-Fu.
Affiliation
  • Lin DS; Department of Pediatrics, Mackay Memorial Hospital, Taipei 10449, Taiwan. lin.ds.md@gmail.com.
  • Huang YW; Department of Medicine and Institute of Biomedical Sciences, Mackay Medical College, New Taipei 25245, Taiwan. lin.ds.md@gmail.com.
  • Ho CS; Department of Medical Research, Mackay Memorial Hospital, Taipei 10449, Taiwan. wendyhuang1219@gmail.com.
  • Hung PL; Department of Pediatrics, Mackay Memorial Hospital, Taipei 10449, Taiwan. pedcsho@gmail.com.
  • Hsu MH; Department of Pediatric Neurology, Kaohsiung Chang Gung Memorial Hospital, and Chang Gung University College of Medicine, Kaohsiung 88301, Taiwan. flora1402@cgmh.org.tw.
  • Wang TJ; Department of Pediatric Neurology, Kaohsiung Chang Gung Memorial Hospital, and Chang Gung University College of Medicine, Kaohsiung 88301, Taiwan. a03peggy@cgmh.org.tw.
  • Wu TY; Department of Laboratory Medicine, Mackay Memorial Hospital, Taipei 10449, Taiwan. dj.wang@mmh.org.tw.
  • Lee TH; Department of Medical Research, Mackay Memorial Hospital, Taipei 10449, Taiwan. linws@mmh.org.tw.
  • Huang ZD; Department of Medical Research, Mackay Memorial Hospital, Taipei 10449, Taiwan. randy.b746mmh@gmail.com.
  • Chang PC; Department of Medical Research, Mackay Memorial Hospital, Taipei 10449, Taiwan. darr.9475@mmh.org.tw.
  • Chiang MF; Department of Information Technology, Mackay Memorial Hospital, Taipei 10449, Taiwan. f1481101@gmail.com.
Cells ; 8(1)2019 01 17.
Article in En | MEDLINE | ID: mdl-30658448
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Autophagy / DNA, Mitochondrial / Mitochondrial Diseases / Induced Pluripotent Stem Cells / Mitophagy / Models, Biological / Mutation Type of study: Prognostic_studies Limits: Humans Language: En Journal: Cells Year: 2019 Document type: Article Affiliation country:
Fulltext
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Print
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PubMed Links
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Autophagy / DNA, Mitochondrial / Mitochondrial Diseases / Induced Pluripotent Stem Cells / Mitophagy / Models, Biological / Mutation Type of study: Prognostic_studies Limits: Humans Language: En Journal: Cells Year: 2019 Document type: Article Affiliation country: