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Destabilization of AETFC through C/EBPα-mediated repression of LYL1 contributes to t(8;21) leukemic cell differentiation.
Zhang, Meng-Meng; Liu, Na; Zhang, Yuan-Liang; Rong, Bowen; Wang, Xiao-Lin; Xu, Chun-Hui; Xie, Yin-Yin; Shen, Shuhong; Zhu, Jiang; Nimer, Stephen D; Chen, Zhu; Chen, Sai-Juan; Roeder, Robert G; Lan, Fei; Wang, Lan; Huang, Qiu-Hua; Sun, Xiao-Jian.
Affiliation
  • Zhang MM; State Key Laboratory of Medical Genomics, Shanghai Institute of Hematology, National Research Center for Translational Medicine, Ruijin Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China.
  • Liu N; CAS Key Laboratory of Tissue Microenvironment and Tumor, Shanghai Institute of Nutrition and Health, Shanghai Institutes for Biological Sciences, University of Chinese Academy of Sciences, Chinese Academy of Sciences, Shanghai, China.
  • Zhang YL; State Key Laboratory of Medical Genomics, Shanghai Institute of Hematology, National Research Center for Translational Medicine, Ruijin Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China.
  • Rong B; Liver Cancer Institute, Zhongshan Hospital, Fudan University, Key Laboratory of Carcinogenesis and Cancer Invasion, Ministry of Education, Key Laboratory of Epigenetics and Metabolism, Ministry of Science and Technology, and Institutes of Biomedical Sciences, Fudan University, Shanghai, China.
  • Wang XL; State Key Laboratory of Medical Genomics, Shanghai Institute of Hematology, National Research Center for Translational Medicine, Ruijin Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China.
  • Xu CH; CAS Key Laboratory of Tissue Microenvironment and Tumor, Shanghai Institute of Nutrition and Health, Shanghai Institutes for Biological Sciences, University of Chinese Academy of Sciences, Chinese Academy of Sciences, Shanghai, China.
  • Xie YY; State Key Laboratory of Medical Genomics, Shanghai Institute of Hematology, National Research Center for Translational Medicine, Ruijin Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China.
  • Shen S; Key Laboratory of Pediatric Hematology and Oncology, Ministry of Health, Department of Pediatric Hematology and Oncology, Shanghai Children's Medical Center, Shanghai Jiao Tong University School of Medicine, Shanghai, China.
  • Zhu J; State Key Laboratory of Medical Genomics, Shanghai Institute of Hematology, National Research Center for Translational Medicine, Ruijin Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China.
  • Nimer SD; Department of Biochemistry and Molecular Biology, Department of Medicine, Sylvester Comprehensive Cancer Center, University of Miami Miller School of Medicine, Miami, FL, USA.
  • Chen Z; State Key Laboratory of Medical Genomics, Shanghai Institute of Hematology, National Research Center for Translational Medicine, Ruijin Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China.
  • Chen SJ; State Key Laboratory of Medical Genomics, Shanghai Institute of Hematology, National Research Center for Translational Medicine, Ruijin Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China.
  • Roeder RG; Laboratory of Biochemistry and Molecular Biology, The Rockefeller University, New York, NY, USA.
  • Lan F; Liver Cancer Institute, Zhongshan Hospital, Fudan University, Key Laboratory of Carcinogenesis and Cancer Invasion, Ministry of Education, Key Laboratory of Epigenetics and Metabolism, Ministry of Science and Technology, and Institutes of Biomedical Sciences, Fudan University, Shanghai, China.
  • Wang L; CAS Key Laboratory of Tissue Microenvironment and Tumor, Shanghai Institute of Nutrition and Health, Shanghai Institutes for Biological Sciences, University of Chinese Academy of Sciences, Chinese Academy of Sciences, Shanghai, China. lwang@sibs.ac.cn.
  • Huang QH; State Key Laboratory of Medical Genomics, Shanghai Institute of Hematology, National Research Center for Translational Medicine, Ruijin Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China. hqh10632@rjh.com.cn.
  • Sun XJ; State Key Laboratory of Medical Genomics, Shanghai Institute of Hematology, National Research Center for Translational Medicine, Ruijin Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China. xjsun@sibs.ac.cn.
Leukemia ; 33(7): 1822-1827, 2019 07.
Article in En | MEDLINE | ID: mdl-30755707
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Translocation, Genetic / Leukemia / Gene Expression Regulation, Neoplastic / Oncogene Proteins, Fusion / Cell Differentiation / CCAAT-Enhancer-Binding Protein-alpha / Basic Helix-Loop-Helix Transcription Factors / Core Binding Factor Alpha 2 Subunit / RUNX1 Translocation Partner 1 Protein / Neoplasm Proteins Type of study: Prognostic_studies Limits: Animals / Humans Language: En Journal: Leukemia Journal subject: HEMATOLOGIA / NEOPLASIAS Year: 2019 Document type: Article Affiliation country:
Fulltext
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Translocation, Genetic / Leukemia / Gene Expression Regulation, Neoplastic / Oncogene Proteins, Fusion / Cell Differentiation / CCAAT-Enhancer-Binding Protein-alpha / Basic Helix-Loop-Helix Transcription Factors / Core Binding Factor Alpha 2 Subunit / RUNX1 Translocation Partner 1 Protein / Neoplasm Proteins Type of study: Prognostic_studies Limits: Animals / Humans Language: En Journal: Leukemia Journal subject: HEMATOLOGIA / NEOPLASIAS Year: 2019 Document type: Article Affiliation country: