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Significance of Autophagy in Dengue Virus Infection: A Brief Review.
Acharya, Bishwanath; Gyeltshen, Sonam; Chaijaroenkul, Wanna; Na-Bangchang, Kesara.
Affiliation
  • Acharya B; Chulabhorn International College of Medicine, Thammasat University, Rangsit Center, Klong Luang, Thailand.
  • Gyeltshen S; Chulabhorn International College of Medicine, Thammasat University, Rangsit Center, Klong Luang, Thailand.
  • Chaijaroenkul W; Chulabhorn International College of Medicine, Thammasat University, Rangsit Center, Klong Luang, Thailand.
  • Na-Bangchang K; Center of Excellence in Pharmacology and Molecular Biology of Malaria and Cholangiocarcinoma, Chulabhorn International College of Medicine, Thammasat University, Rangsit Center, Klong Luang, Thailand.
Am J Trop Med Hyg ; 100(4): 783-790, 2019 04.
Article in En | MEDLINE | ID: mdl-30761986
Dengue virus (DENV) causes asymptomatic to severe life-threatening infections and affects millions of people worldwide. Autophagy, a cellular degradative pathway, has both proviral and antiviral functions. Dengue virus triggers the autophagy pathway for the successful replication of its genome. However, the exact mechanism and the viral factors involved in activating this pathway remain unclear. This review summarizes the existing knowledge on the mechanism of autophagy induction and its significance during DENV infection.
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Autophagy / Dengue / Dengue Virus Limits: Humans Language: En Journal: Am J Trop Med Hyg Year: 2019 Document type: Article Affiliation country: Country of publication:
Fulltext
Add to My VHL
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PubMed Links
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Autophagy / Dengue / Dengue Virus Limits: Humans Language: En Journal: Am J Trop Med Hyg Year: 2019 Document type: Article Affiliation country: Country of publication: