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G-quadruplex DNA drives genomic instability and represents a targetable molecular abnormality in ATRX-deficient malignant glioma.
Wang, Yuxiang; Yang, Jie; Wild, Aaron T; Wu, Wei H; Shah, Rachna; Danussi, Carla; Riggins, Gregory J; Kannan, Kasthuri; Sulman, Erik P; Chan, Timothy A; Huse, Jason T.
Affiliation
  • Wang Y; Human Oncology and Pathogenesis Program, Memorial Sloan-Kettering Cancer Center, New York, NY, 10065, USA.
  • Yang J; Department of Radation Oncology, University of Texas MD Anderson Cancer Center, Houston, TX, 77030, USA.
  • Wild AT; Human Oncology and Pathogenesis Program, Memorial Sloan-Kettering Cancer Center, New York, NY, 10065, USA.
  • Wu WH; Human Oncology and Pathogenesis Program, Memorial Sloan-Kettering Cancer Center, New York, NY, 10065, USA.
  • Shah R; Human Oncology and Pathogenesis Program, Memorial Sloan-Kettering Cancer Center, New York, NY, 10065, USA.
  • Danussi C; Department of Translational Molecular Pathology, University of Texas MD Anderson Cancer Center, Houston, TX, 77030, USA.
  • Riggins GJ; Departments of Neurosurgery, Oncology, and Genetic Medicine, Johns Hopkins School of Medicine, Baltimore, MD, 21231, USA.
  • Kannan K; Department of Pathology, New York University School of Medicine, New York, NY, 10016, USA.
  • Sulman EP; Department of Radation Oncology, University of Texas MD Anderson Cancer Center, Houston, TX, 77030, USA.
  • Chan TA; Department of Pathology, University of Texas MD Anderson Cancer Center, Houston, TX, 77030, USA.
  • Huse JT; Human Oncology and Pathogenesis Program, Memorial Sloan-Kettering Cancer Center, New York, NY, 10065, USA.
Nat Commun ; 10(1): 943, 2019 02 26.
Article in En | MEDLINE | ID: mdl-30808951
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Brain Neoplasms / G-Quadruplexes / X-linked Nuclear Protein / Glioma Type of study: Prognostic_studies Limits: Animals / Humans Language: En Journal: Nat Commun Journal subject: BIOLOGIA / CIENCIA Year: 2019 Document type: Article Affiliation country:
Fulltext
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Brain Neoplasms / G-Quadruplexes / X-linked Nuclear Protein / Glioma Type of study: Prognostic_studies Limits: Animals / Humans Language: En Journal: Nat Commun Journal subject: BIOLOGIA / CIENCIA Year: 2019 Document type: Article Affiliation country: