Sinus venosus incorporation: contentious issues and operational criteria for developmental and evolutionary studies.
J Anat
; 234(5): 583-591, 2019 05.
Article
in En
| MEDLINE
| ID: mdl-30861129
ABSTRACT
The sinus venosus is a cardiac chamber upstream of the right atrium that harbours the dominant cardiac pacemaker. During human heart development, the sinus venosus becomes incorporated into the right atrium. However, from the literature it is not possible to deduce the characteristics and importance of this process of incorporation, due to inconsistent terminology and definitions in the description of multiple lines of evidence. We reviewed the literature regarding the incorporation of the sinus venosus and included novel electrophysiological data. Most mammals that have an incorporated sinus venosus show a loss of a functional valve guard of the superior caval vein together with a loss of the electrical sinuatrial delay between the sinus venosus and the right atrium. However, these processes are not necessarily intertwined and in a few species only the sinuatrial delay may be lost. Sinus venosus incorporation can be characterised as the loss of the sinuatrial delay of which the anatomical and molecular underpinnings are not yet understood.
Key words
Full text:
1
Collection:
01-internacional
Database:
MEDLINE
Main subject:
Sinoatrial Node
/
Heart
/
Heart Atria
Limits:
Animals
/
Humans
Language:
En
Journal:
J Anat
Year:
2019
Document type:
Article
Affiliation country: