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Targeted degradation of aberrant tau in frontotemporal dementia patient-derived neuronal cell models.
Silva, M Catarina; Ferguson, Fleur M; Cai, Quan; Donovan, Katherine A; Nandi, Ghata; Patnaik, Debasis; Zhang, Tinghu; Huang, Hai-Tsang; Lucente, Diane E; Dickerson, Bradford C; Mitchison, Timothy J; Fischer, Eric S; Gray, Nathanael S; Haggarty, Stephen J.
Affiliation
  • Silva MC; Chemical Neurobiology Laboratory, Center for Genomic Medicine, Massachusetts General Hospital, Harvard Medical School, Boston, United States.
  • Ferguson FM; Department of Neurology, Massachusetts General Hospital, Harvard Medical School, Boston, United States.
  • Cai Q; Department of Psychiatry, Massachusetts General Hospital, Harvard Medical School, Boston, United States.
  • Donovan KA; Department of Cancer Biology, Dana-Farber Cancer Institute, Boston, United States.
  • Nandi G; Department of Biological Chemistry and Molecular Pharmacology, Harvard Medical School, Boston, United States.
  • Patnaik D; Department of Cancer Biology, Dana-Farber Cancer Institute, Boston, United States.
  • Zhang T; Department of Biological Chemistry and Molecular Pharmacology, Harvard Medical School, Boston, United States.
  • Huang HT; Department of Cancer Biology, Dana-Farber Cancer Institute, Boston, United States.
  • Lucente DE; Department of Biological Chemistry and Molecular Pharmacology, Harvard Medical School, Boston, United States.
  • Dickerson BC; Chemical Neurobiology Laboratory, Center for Genomic Medicine, Massachusetts General Hospital, Harvard Medical School, Boston, United States.
  • Mitchison TJ; Department of Neurology, Massachusetts General Hospital, Harvard Medical School, Boston, United States.
  • Fischer ES; Department of Psychiatry, Massachusetts General Hospital, Harvard Medical School, Boston, United States.
  • Gray NS; Chemical Neurobiology Laboratory, Center for Genomic Medicine, Massachusetts General Hospital, Harvard Medical School, Boston, United States.
  • Haggarty SJ; Department of Neurology, Massachusetts General Hospital, Harvard Medical School, Boston, United States.
Elife ; 82019 03 25.
Article in En | MEDLINE | ID: mdl-30907729
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Tau Proteins / Neuroprotective Agents / Tauopathies / Frontotemporal Dementia / Proteolysis / Neurons Limits: Humans Language: En Journal: Elife Year: 2019 Document type: Article Affiliation country: Country of publication:
Fulltext
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Tau Proteins / Neuroprotective Agents / Tauopathies / Frontotemporal Dementia / Proteolysis / Neurons Limits: Humans Language: En Journal: Elife Year: 2019 Document type: Article Affiliation country: Country of publication: