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Eosinophil peroxidase oxidizes isoniazid to form the active metabolite against M. tuberculosis, isoniazid-NAD.
Babu, Dinesh; Morgan, Andrew G; Reiz, Béla; Whittal, Randy M; Almas, Sarah; Lacy, Paige; Siraki, Arno G.
Affiliation
  • Babu D; Faculty of Pharmacy and Pharmaceutical Sciences, Katz Group Centre for Pharmacy & Health Research, University of Alberta, Edmonton, AB, Canada.
  • Morgan AG; Faculty of Pharmacy and Pharmaceutical Sciences, Katz Group Centre for Pharmacy & Health Research, University of Alberta, Edmonton, AB, Canada.
  • Reiz B; Department of Chemistry, Faculty of Sciences, University of Alberta, Edmonton, AB, Canada.
  • Whittal RM; Department of Chemistry, Faculty of Sciences, University of Alberta, Edmonton, AB, Canada.
  • Almas S; Pulmonary Research Group, Department of Medicine, Faculty of Medicine & Dentistry, University of Alberta, Edmonton, AB, Canada.
  • Lacy P; Pulmonary Research Group, Department of Medicine, Faculty of Medicine & Dentistry, University of Alberta, Edmonton, AB, Canada.
  • Siraki AG; Faculty of Pharmacy and Pharmaceutical Sciences, Katz Group Centre for Pharmacy & Health Research, University of Alberta, Edmonton, AB, Canada. Electronic address: siraki@ualberta.ca.
Chem Biol Interact ; 305: 48-53, 2019 May 25.
Article in En | MEDLINE | ID: mdl-30922765
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Eosinophil Peroxidase / Eosinophils / Isoniazid / NAD Limits: Humans Language: En Journal: Chem Biol Interact Year: 2019 Document type: Article Affiliation country: Country of publication:
Fulltext
Add to My VHL
Print
XML
PubMed Links
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Eosinophil Peroxidase / Eosinophils / Isoniazid / NAD Limits: Humans Language: En Journal: Chem Biol Interact Year: 2019 Document type: Article Affiliation country: Country of publication: