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An Asymmetric Opening of HIV-1 Envelope Mediates Antibody-Dependent Cellular Cytotoxicity.
Alsahafi, Nirmin; Bakouche, Nordine; Kazemi, Mohsen; Richard, Jonathan; Ding, Shilei; Bhattacharyya, Sudipta; Das, Durba; Anand, Sai Priya; Prévost, Jérémie; Tolbert, William D; Lu, Hong; Medjahed, Halima; Gendron-Lepage, Gabrielle; Ortega Delgado, Gloria Gabrielle; Kirk, Sharon; Melillo, Bruno; Mothes, Walther; Sodroski, Joseph; Smith, Amos B; Kaufmann, Daniel E; Wu, Xueling; Pazgier, Marzena; Rouiller, Isabelle; Finzi, Andrés; Munro, James B.
Affiliation
  • Alsahafi N; Centre de Recherche du CHUM, Montreal, QC, Canada; Department of Microbiology and Immunology, McGill University, Montreal, QC, Canada.
  • Bakouche N; Department of Molecular Biology and Microbiology, Tufts University School of Medicine, Boston, MA, USA.
  • Kazemi M; Department of Biochemistry and Molecular Biology and Bio21 Molecular Science and Biotechnology Institute, The University of Melbourne, Parkville, VIC, Australia.
  • Richard J; Centre de Recherche du CHUM, Montreal, QC, Canada; Département de Microbiologie, Infectiologie et Immunologie, Université de Montréal, Montreal, QC, Canada.
  • Ding S; Centre de Recherche du CHUM, Montreal, QC, Canada; Département de Microbiologie, Infectiologie et Immunologie, Université de Montréal, Montreal, QC, Canada.
  • Bhattacharyya S; Department of Biochemistry and Molecular Biology and Bio21 Molecular Science and Biotechnology Institute, The University of Melbourne, Parkville, VIC, Australia.
  • Das D; Department of Biochemistry and Molecular Biology and Bio21 Molecular Science and Biotechnology Institute, The University of Melbourne, Parkville, VIC, Australia.
  • Anand SP; Centre de Recherche du CHUM, Montreal, QC, Canada; Department of Microbiology and Immunology, McGill University, Montreal, QC, Canada.
  • Prévost J; Centre de Recherche du CHUM, Montreal, QC, Canada; Département de Microbiologie, Infectiologie et Immunologie, Université de Montréal, Montreal, QC, Canada.
  • Tolbert WD; Infectious Diseases Division, Uniformed Services University of the Health Sciences, Bethesda, MD, USA.
  • Lu H; Aaron Diamond AIDS Research Center, Affiliate of The Rockefeller University, New York, NY, USA.
  • Medjahed H; Centre de Recherche du CHUM, Montreal, QC, Canada.
  • Gendron-Lepage G; Centre de Recherche du CHUM, Montreal, QC, Canada.
  • Ortega Delgado GG; Centre de Recherche du CHUM, Montreal, QC, Canada.
  • Kirk S; Department of Chemistry, School of Arts and Sciences, University of Pennsylvania, Philadelphia, PA 19104-6323, USA.
  • Melillo B; Department of Chemistry, School of Arts and Sciences, University of Pennsylvania, Philadelphia, PA 19104-6323, USA.
  • Mothes W; Department of Microbial Pathogenesis, Yale University School of Medicine, New Haven, CT 06536, USA.
  • Sodroski J; Department of Cancer Immunology and Virology, Dana-Farber Cancer Institute, Boston, MA 02215, USA; Department of Microbiology and Immunobiology, Harvard Medical School, Boston, MA 02115, USA; Department of Immunology and Infectious Diseases, Harvard T.H. Chan School of Public Health, Boston, MA 0211
  • Smith AB; Department of Chemistry, School of Arts and Sciences, University of Pennsylvania, Philadelphia, PA 19104-6323, USA.
  • Kaufmann DE; Centre de Recherche du CHUM, Montreal, QC, Canada; Département de Microbiologie, Infectiologie et Immunologie, Université de Montréal, Montreal, QC, Canada; Department of Medicine, Université de Montréal, Montreal, QC, Canada; Center for HIV/AIDS Vaccine Immunology and Immunogen Discovery, The Scrip
  • Wu X; Aaron Diamond AIDS Research Center, Affiliate of The Rockefeller University, New York, NY, USA.
  • Pazgier M; Infectious Diseases Division, Uniformed Services University of the Health Sciences, Bethesda, MD, USA.
  • Rouiller I; Department of Biochemistry and Molecular Biology and Bio21 Molecular Science and Biotechnology Institute, The University of Melbourne, Parkville, VIC, Australia. Electronic address: isabelle.rouiller@unimelb.edu.au.
  • Finzi A; Centre de Recherche du CHUM, Montreal, QC, Canada; Department of Microbiology and Immunology, McGill University, Montreal, QC, Canada; Département de Microbiologie, Infectiologie et Immunologie, Université de Montréal, Montreal, QC, Canada. Electronic address: andres.finzi@umontreal.ca.
  • Munro JB; Department of Molecular Biology and Microbiology, Tufts University School of Medicine, Boston, MA, USA. Electronic address: james.munro@tufts.edu.
Cell Host Microbe ; 25(4): 578-587.e5, 2019 Apr 10.
Article in En | MEDLINE | ID: mdl-30974085

Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: HIV Antibodies / CD4-Positive T-Lymphocytes / HIV-1 / Env Gene Products, Human Immunodeficiency Virus / Antibody-Dependent Cell Cytotoxicity Limits: Humans Language: En Journal: Cell Host Microbe Journal subject: MICROBIOLOGIA Year: 2019 Document type: Article Affiliation country: Country of publication:

Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: HIV Antibodies / CD4-Positive T-Lymphocytes / HIV-1 / Env Gene Products, Human Immunodeficiency Virus / Antibody-Dependent Cell Cytotoxicity Limits: Humans Language: En Journal: Cell Host Microbe Journal subject: MICROBIOLOGIA Year: 2019 Document type: Article Affiliation country: Country of publication: