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Oxidized low-density lipoprotein (oxLDL) supports Mycobacterium tuberculosis survival in macrophages by inducing lysosomal dysfunction.
Vrieling, Frank; Wilson, Louis; Rensen, Patrick C N; Walzl, Gerhard; Ottenhoff, Tom H M; Joosten, Simone A.
Affiliation
  • Vrieling F; Department of Infectious Diseases, Leiden University Medical Center, Albinusdreef 2, ZA Leiden, The Netherlands.
  • Wilson L; Department of Infectious Diseases, Leiden University Medical Center, Albinusdreef 2, ZA Leiden, The Netherlands.
  • Rensen PCN; Department of Medicine, Division of Endocrinology, Leiden University Medical Center, Albinusdreef 2, ZA Leiden, The Netherlands.
  • Walzl G; DST/NRF Center of Excellence for Biomedical Tuberculosis Research, SA MRC Center for TB Research, Division of Molecular Biology and Human Genetics, Department of Biomedical Sciences, Faculty of Medicine and Health Sciences Stellenbosch University, Francie van Zijl Drive, Tygerberg, Cape Town, South
  • Ottenhoff THM; Department of Infectious Diseases, Leiden University Medical Center, Albinusdreef 2, ZA Leiden, The Netherlands.
  • Joosten SA; Department of Infectious Diseases, Leiden University Medical Center, Albinusdreef 2, ZA Leiden, The Netherlands.
PLoS Pathog ; 15(4): e1007724, 2019 04.
Article in En | MEDLINE | ID: mdl-30998773

Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Tuberculosis / Diabetes Mellitus, Type 2 / Lipoproteins, LDL / Lysosomes / Macrophages / Mycobacterium tuberculosis Type of study: Etiology_studies / Incidence_studies / Observational_studies / Prognostic_studies Limits: Humans Language: En Journal: PLoS Pathog Year: 2019 Document type: Article Affiliation country: Country of publication:

Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Tuberculosis / Diabetes Mellitus, Type 2 / Lipoproteins, LDL / Lysosomes / Macrophages / Mycobacterium tuberculosis Type of study: Etiology_studies / Incidence_studies / Observational_studies / Prognostic_studies Limits: Humans Language: En Journal: PLoS Pathog Year: 2019 Document type: Article Affiliation country: Country of publication: