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Hsp90 middle domain phosphorylation initiates a complex conformational program to recruit the ATPase-stimulating cochaperone Aha1.
Xu, Wanping; Beebe, Kristin; Chavez, Juan D; Boysen, Marta; Lu, YinYing; Zuehlke, Abbey D; Keramisanou, Dimitra; Trepel, Jane B; Prodromou, Christosomos; Mayer, Matthias P; Bruce, James E; Gelis, Ioannis; Neckers, Len.
Affiliation
  • Xu W; Urologic Oncology Branch, National Cancer Institute, Bethesda, MD, 20892, USA.
  • Beebe K; Urologic Oncology Branch, National Cancer Institute, Bethesda, MD, 20892, USA.
  • Chavez JD; Department of Genome Sciences, University of Washington School of Medicine, Seattle, WA, 98195, USA.
  • Boysen M; Center for Molecular Biology, University of Heidelberg, 69120, Heidelberg, Germany.
  • Lu Y; Urologic Oncology Branch, National Cancer Institute, Bethesda, MD, 20892, USA.
  • Zuehlke AD; Center for Therapeutic Research of Hepatocarcinoma, Beijing 302 Hospital, 100 Xi Si Huan Middle Road, 100039, Beijing, China.
  • Keramisanou D; Urologic Oncology Branch, National Cancer Institute, Bethesda, MD, 20892, USA.
  • Trepel JB; Department of Chemistry, University of South Florida, Tampa, FL, 33620, USA.
  • Prodromou C; Developmental Therapeutics Branch, National Cancer Institute, Bethesda, MD, 20892, USA.
  • Mayer MP; Genome and Damage Stability Center, University of Sussex, Brighton, BN1 9RH, UK.
  • Bruce JE; Center for Molecular Biology, University of Heidelberg, 69120, Heidelberg, Germany.
  • Gelis I; Department of Genome Sciences, University of Washington School of Medicine, Seattle, WA, 98195, USA.
  • Neckers L; Department of Chemistry, University of South Florida, Tampa, FL, 33620, USA.
Nat Commun ; 10(1): 2574, 2019 06 12.
Article in En | MEDLINE | ID: mdl-31189925
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Adenosine Triphosphatases / Molecular Chaperones / HSP90 Heat-Shock Proteins / Protein Domains Limits: Humans Language: En Journal: Nat Commun Journal subject: BIOLOGIA / CIENCIA Year: 2019 Document type: Article Affiliation country: Country of publication:
Fulltext
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Adenosine Triphosphatases / Molecular Chaperones / HSP90 Heat-Shock Proteins / Protein Domains Limits: Humans Language: En Journal: Nat Commun Journal subject: BIOLOGIA / CIENCIA Year: 2019 Document type: Article Affiliation country: Country of publication: