Functional boundaries in the human cerebellum revealed by a multi-domain task battery.
Nat Neurosci
; 22(8): 1371-1378, 2019 08.
Article
in En
| MEDLINE
| ID: mdl-31285616
ABSTRACT
There is compelling evidence that the human cerebellum is engaged in a wide array of motor and cognitive tasks. A fundamental question centers on whether the cerebellum is organized into distinct functional subregions. To address this question, we employed a rich task battery designed to tap into a broad range of cognitive processes. During four functional MRI sessions, participants performed a battery of 26 diverse tasks comprising 47 unique conditions. Using the data from this multi-domain task battery, we derived a comprehensive functional parcellation of the cerebellar cortex and evaluated it by predicting functional boundaries in a novel set of tasks. The new parcellation successfully identified distinct functional subregions, providing significant improvements over existing parcellations derived from task-free data. Lobular boundaries, commonly used to summarize functional data, did not coincide with functional subdivisions. The new parcellation provides a functional atlas to guide future neuroimaging studies.
Full text:
1
Collection:
01-internacional
Database:
MEDLINE
Main subject:
Cerebellum
Limits:
Adult
/
Female
/
Humans
/
Male
Language:
En
Journal:
Nat Neurosci
Journal subject:
NEUROLOGIA
Year:
2019
Document type:
Article
Affiliation country: