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Treatment of rat thyrocytes in vitro with cathepsin B and L inhibitors results in disruption of primary cilia leading to redistribution of the trace amine associated receptor 1 to the endoplasmic reticulum.
Szumska, Joanna; Batool, Zaina; Al-Hashimi, Alaa; Venugopalan, Vaishnavi; Skripnik, Vladislav; Schaschke, Norbert; Bogyo, Matthew; Brix, Klaudia.
Affiliation
  • Szumska J; Department of Life Sciences and Chemistry, Jacobs University Bremen, Campus Ring 1, 28759 Bremen, Germany.
  • Batool Z; Department of Life Sciences and Chemistry, Jacobs University Bremen, Campus Ring 1, 28759 Bremen, Germany.
  • Al-Hashimi A; Department of Life Sciences and Chemistry, Jacobs University Bremen, Campus Ring 1, 28759 Bremen, Germany.
  • Venugopalan V; Department of Life Sciences and Chemistry, Jacobs University Bremen, Campus Ring 1, 28759 Bremen, Germany.
  • Skripnik V; Department of Life Sciences and Chemistry, Jacobs University Bremen, Campus Ring 1, 28759 Bremen, Germany.
  • Schaschke N; Fakultät für Chemie, Hochschule Aalen, 73430 Aalen, Germany.
  • Bogyo M; Department of Pathology, Stanford University School of Medicine, Stanford, CA, USA.
  • Brix K; Department of Life Sciences and Chemistry, Jacobs University Bremen, Campus Ring 1, 28759 Bremen, Germany. Electronic address: k.brix@jacobs-university.de.
Biochimie ; 166: 270-285, 2019 Nov.
Article in En | MEDLINE | ID: mdl-31302164

Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Cathepsin B / Cilia / Receptors, G-Protein-Coupled / Endoplasmic Reticulum / Cathepsin L / Thyroid Epithelial Cells Type of study: Risk_factors_studies Limits: Animals Language: En Journal: Biochimie Year: 2019 Document type: Article Affiliation country: Country of publication:

Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Cathepsin B / Cilia / Receptors, G-Protein-Coupled / Endoplasmic Reticulum / Cathepsin L / Thyroid Epithelial Cells Type of study: Risk_factors_studies Limits: Animals Language: En Journal: Biochimie Year: 2019 Document type: Article Affiliation country: Country of publication: