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An Angle on MK2 Inhibition-Optimization and Evaluation of Prevention of Activation Inhibitors.
Hedström, Ulf; Norberg, Monica; Evertsson, Emma; Lever, Sarah R; Munck Af Rosenschöld, Magnus; Lönn, Hans; Bold, Peter; Käck, Helena; Berntsson, Pia; Vinblad, Johanna; Liu, Jianming; Welinder, Anette; Karlsson, Johan; Snijder, Arjan; Pardali, Katerina; Andersson, Ulf; Davis, Andrew M; Mogemark, Mickael.
Affiliation
  • Hedström U; Early Respiratory, Inflammation and Autoimmunity, R&D Biopharmaceuticals, AstraZeneca, Gothenburg, Pepparedsleden 1, 431 83, Mölndal, Sweden.
  • Norberg M; Early Respiratory, Inflammation and Autoimmunity, R&D Biopharmaceuticals, AstraZeneca, Gothenburg, Pepparedsleden 1, 431 83, Mölndal, Sweden.
  • Evertsson E; Early Respiratory, Inflammation and Autoimmunity, R&D Biopharmaceuticals, AstraZeneca, Gothenburg, Pepparedsleden 1, 431 83, Mölndal, Sweden.
  • Lever SR; Early Respiratory, Inflammation and Autoimmunity, R&D Biopharmaceuticals, AstraZeneca, Gothenburg, Pepparedsleden 1, 431 83, Mölndal, Sweden.
  • Munck Af Rosenschöld M; Early Respiratory, Inflammation and Autoimmunity, R&D Biopharmaceuticals, AstraZeneca, Gothenburg, Pepparedsleden 1, 431 83, Mölndal, Sweden.
  • Lönn H; Early Respiratory, Inflammation and Autoimmunity, R&D Biopharmaceuticals, AstraZeneca, Gothenburg, Pepparedsleden 1, 431 83, Mölndal, Sweden.
  • Bold P; Early Respiratory, Inflammation and Autoimmunity, R&D Biopharmaceuticals, AstraZeneca, Gothenburg, Pepparedsleden 1, 431 83, Mölndal, Sweden.
  • Käck H; Discovery Sciences, R&D Biopharmaceuticals, AstraZeneca, Gothenburg, Pepparedsleden 1, 431 83, Mölndal, Sweden.
  • Berntsson P; Early Respiratory, Inflammation and Autoimmunity, R&D Biopharmaceuticals, AstraZeneca, Gothenburg, Pepparedsleden 1, 431 83, Mölndal, Sweden.
  • Vinblad J; Early Respiratory, Inflammation and Autoimmunity, R&D Biopharmaceuticals, AstraZeneca, Gothenburg, Pepparedsleden 1, 431 83, Mölndal, Sweden.
  • Liu J; Discovery Sciences, R&D Biopharmaceuticals, AstraZeneca, Gothenburg, Pepparedsleden 1, 431 83, Mölndal, Sweden.
  • Welinder A; Pharmaceutical Technology and Development, Operations, AstraZeneca, Gothenburg, Pepparedsleden 1, 431 83, Mölndal, Sweden.
  • Karlsson J; Discovery Sciences, R&D Biopharmaceuticals, AstraZeneca, Gothenburg, Pepparedsleden 1, 431 83, Mölndal, Sweden.
  • Snijder A; Discovery Sciences, R&D Biopharmaceuticals, AstraZeneca, Gothenburg, Pepparedsleden 1, 431 83, Mölndal, Sweden.
  • Pardali K; Early Respiratory, Inflammation and Autoimmunity, R&D Biopharmaceuticals, AstraZeneca, Gothenburg, Pepparedsleden 1, 431 83, Mölndal, Sweden.
  • Andersson U; Clinical Pharmacology and Safety Sciences, R&D Biopharmaceuticals, AstraZeneca, Gothenburg, Pepparedsleden 1, 431 83, Mölndal, Sweden.
  • Davis AM; Early Respiratory, Inflammation and Autoimmunity, R&D Biopharmaceuticals, AstraZeneca, Gothenburg, Pepparedsleden 1, 431 83, Mölndal, Sweden.
  • Mogemark M; Clinical Pharmacology and Safety Sciences, R&D Biopharmaceuticals, AstraZeneca, Gothenburg, Pepparedsleden 1, 431 83, Mölndal, Sweden.
ChemMedChem ; 14(19): 1701-1709, 2019 10 04.
Article in En | MEDLINE | ID: mdl-31325352
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Pyrazoles / Protein Serine-Threonine Kinases / Intracellular Signaling Peptides and Proteins / Mitogen-Activated Protein Kinase 14 / Protein Kinase Inhibitors / Enzyme Activation / Imidazoles / Anti-Inflammatory Agents Limits: Humans Language: En Journal: ChemMedChem Journal subject: FARMACOLOGIA / QUIMICA Year: 2019 Document type: Article Affiliation country:
Fulltext
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Pyrazoles / Protein Serine-Threonine Kinases / Intracellular Signaling Peptides and Proteins / Mitogen-Activated Protein Kinase 14 / Protein Kinase Inhibitors / Enzyme Activation / Imidazoles / Anti-Inflammatory Agents Limits: Humans Language: En Journal: ChemMedChem Journal subject: FARMACOLOGIA / QUIMICA Year: 2019 Document type: Article Affiliation country: