Your browser doesn't support javascript.
loading
Cryptic pocket formation underlies allosteric modulator selectivity at muscarinic GPCRs.
Hollingsworth, Scott A; Kelly, Brendan; Valant, Celine; Michaelis, Jordan Arthur; Mastromihalis, Olivia; Thompson, Geoff; Venkatakrishnan, A J; Hertig, Samuel; Scammells, Peter J; Sexton, Patrick M; Felder, Christian C; Christopoulos, Arthur; Dror, Ron O.
Affiliation
  • Hollingsworth SA; Departments of Computer Science, Molecular and Cellular Physiology, and Structural Biology, and Institute for Computational and Mathematical Engineering, Stanford University, Stanford, CA, 94305, USA.
  • Kelly B; Merck & Co., Boston, MA, 02110, USA.
  • Valant C; Departments of Computer Science, Molecular and Cellular Physiology, and Structural Biology, and Institute for Computational and Mathematical Engineering, Stanford University, Stanford, CA, 94305, USA. kellybj86@gmail.com.
  • Michaelis JA; Drug Discovery Biology, Monash Institute of Pharmaceutical Sciences and Department of Pharmacology, Monash University, Parkville, VIC, 3052, Australia.
  • Mastromihalis O; Drug Discovery Biology, Monash Institute of Pharmaceutical Sciences and Department of Pharmacology, Monash University, Parkville, VIC, 3052, Australia.
  • Thompson G; Drug Discovery Biology, Monash Institute of Pharmaceutical Sciences and Department of Pharmacology, Monash University, Parkville, VIC, 3052, Australia.
  • Venkatakrishnan AJ; Drug Discovery Biology, Monash Institute of Pharmaceutical Sciences and Department of Pharmacology, Monash University, Parkville, VIC, 3052, Australia.
  • Hertig S; Departments of Computer Science, Molecular and Cellular Physiology, and Structural Biology, and Institute for Computational and Mathematical Engineering, Stanford University, Stanford, CA, 94305, USA.
  • Scammells PJ; Departments of Computer Science, Molecular and Cellular Physiology, and Structural Biology, and Institute for Computational and Mathematical Engineering, Stanford University, Stanford, CA, 94305, USA.
  • Sexton PM; Drug Discovery Biology, Monash Institute of Pharmaceutical Sciences and Department of Pharmacology, Monash University, Parkville, VIC, 3052, Australia.
  • Felder CC; Drug Discovery Biology, Monash Institute of Pharmaceutical Sciences and Department of Pharmacology, Monash University, Parkville, VIC, 3052, Australia.
  • Christopoulos A; Eli Lilly and Co., Neuroscience, Lilly Corporate Center, Indianapolis, IN, 46285, USA.
  • Dror RO; Karuna Pharmaceuticals, Inc., South San Francisco, CA, 94080, USA.
Nat Commun ; 10(1): 3289, 2019 07 23.
Article in En | MEDLINE | ID: mdl-31337749
Subject(s)
Fulltext
Add to My VHL
Print
XML
PubMed Links
Search on Google

Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Receptors, G-Protein-Coupled / Receptor, Muscarinic M1 Type of study: Prognostic_studies Language: En Journal: Nat Commun Journal subject: BIOLOGIA / CIENCIA Year: 2019 Document type: Article Affiliation country:
Fulltext
Add to My VHL
Print
XML
PubMed Links
Search on Google

Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Receptors, G-Protein-Coupled / Receptor, Muscarinic M1 Type of study: Prognostic_studies Language: En Journal: Nat Commun Journal subject: BIOLOGIA / CIENCIA Year: 2019 Document type: Article Affiliation country: