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Regulatory T cells from patients with end-stage organ disease can be isolated, expanded and cryopreserved according good manufacturing practice improving their function.
Ulbar, Francesca; Montemurro, Tiziana; Jofra, Tatiana; Capri, Miriam; Comai, Giorgia; Bertuzzo, Valentina; Lavazza, Cristiana; Mandelli, Alessandra; Viganò, Mariele; Budelli, Silvia; Bacalini, Maria Giulia; Pirazzini, Chiara; Garagnani, Paolo; Giudice, Valeria; Sollazzo, Daria; Curti, Antonio; Arpinati, Mario; La Manna, Gaetano; Cescon, Matteo; Pinna, Antonio Daniele; Franceschi, Claudio; Battaglia, Manuela; Giordano, Rosaria; Catani, Lucia; Lemoli, Roberto Massimo.
Affiliation
  • Ulbar F; Department of Experimental, Diagnostic and Specialty Medicine, Institute of Hematology "L. e A. Seràgnoli", University of Bologna, Bologna, Italy.
  • Montemurro T; Cell Factory, Unit of Cellular Therapy and Cryobiology, Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico, Milan, Italy.
  • Jofra T; Diabetes Research Institute, IRCCS San Raffaele Scientific Institute, Milan, Italy.
  • Capri M; Department of Experimental, Diagnostic and Specialty Medicine, University of Bologna, Bologna, Italy.
  • Comai G; Nephrology Dialysis and Renal Transplant Unit, Department of Experimental Diagnostic and Specialty Medicine, University of Bologna, Bologna, Italy.
  • Bertuzzo V; Department of Medical and Surgical Sciences, University of Bologna, Bologna, Italy.
  • Lavazza C; Cell Factory, Unit of Cellular Therapy and Cryobiology, Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico, Milan, Italy.
  • Mandelli A; Diabetes Research Institute, IRCCS San Raffaele Scientific Institute, Milan, Italy.
  • Viganò M; Cell Factory, Unit of Cellular Therapy and Cryobiology, Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico, Milan, Italy.
  • Budelli S; Cell Factory, Unit of Cellular Therapy and Cryobiology, Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico, Milan, Italy.
  • Bacalini MG; EPIGET LAB, Department of Clinical Sciences and Community Health, University of Milan, Milan, Italy.
  • Pirazzini C; IRCCS Istituto delle Scienze Neurologiche di Bologna, Bologna, Italy.
  • Garagnani P; IRCCS Istituto delle Scienze Neurologiche di Bologna, Bologna, Italy.
  • Giudice V; Department of Experimental, Diagnostic and Specialty Medicine, University of Bologna, Bologna, Italy.
  • Sollazzo D; Clinical Chemistry, Department of Laboratory Medicine, Karolinska Institutet at Huddinge University Hospital, Stockholm, Sweden.
  • Curti A; Laboratory of Cell Biology, Rizzoli Orthopaedic Institute, Bologna, Italy.
  • Arpinati M; Unit of Bologna, CNR Institute of Molecular Genetics, Bologna, Italy.
  • La Manna G; Center for Applied Biomedical Research (CRBA), St. Orsola-Malpighi University Hospital, Bologna, Italy.
  • Cescon M; Azienda Ospedaliero-Universitaria di Bologna S. Orsola-Malpighi, Bologna, Italy.
  • Pinna AD; Department of Experimental, Diagnostic and Specialty Medicine, Institute of Hematology "L. e A. Seràgnoli", University of Bologna, Bologna, Italy.
  • Franceschi C; Department of Experimental, Diagnostic and Specialty Medicine, Institute of Hematology "L. e A. Seràgnoli", University of Bologna, Bologna, Italy.
  • Battaglia M; Department of Experimental, Diagnostic and Specialty Medicine, Institute of Hematology "L. e A. Seràgnoli", University of Bologna, Bologna, Italy.
  • Giordano R; Nephrology Dialysis and Renal Transplant Unit, Department of Experimental Diagnostic and Specialty Medicine, University of Bologna, Bologna, Italy.
  • Catani L; Department of Medical and Surgical Sciences, University of Bologna, Bologna, Italy.
  • Lemoli RM; Department of Medical and Surgical Sciences, University of Bologna, Bologna, Italy.
J Transl Med ; 17(1): 250, 2019 08 05.
Article in En | MEDLINE | ID: mdl-31383037

Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Cryopreservation / T-Lymphocytes, Regulatory / Kidney Failure, Chronic / Liver Diseases Type of study: Guideline / Prognostic_studies Limits: Adult / Aged / Animals / Female / Humans / Male / Middle aged Language: En Journal: J Transl Med Year: 2019 Document type: Article Affiliation country:

Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Cryopreservation / T-Lymphocytes, Regulatory / Kidney Failure, Chronic / Liver Diseases Type of study: Guideline / Prognostic_studies Limits: Adult / Aged / Animals / Female / Humans / Male / Middle aged Language: En Journal: J Transl Med Year: 2019 Document type: Article Affiliation country: