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Discovery and Biological Evaluations of Halogenated 2,4-Diphenyl Indeno[1,2-b]pyridinol Derivatives as Potent Topoisomerase IIα-Targeted Chemotherapeutic Agents for Breast Cancer.
Kadayat, Tara Man; Park, Seojeong; Shrestha, Aarajana; Jo, Hyunji; Hwang, Soo-Yeon; Katila, Pramila; Shrestha, Ritina; Nepal, Mahesh Raj; Noh, Keumhan; Kim, Sang Kyoon; Koh, Woo-Suk; Kim, Kil Soo; Jeon, Yong Hyun; Jeong, Tae Cheon; Kwon, Youngjoo; Lee, Eung-Seok.
Affiliation
  • Kadayat TM; College of Pharmacy , Yeungnam University , Gyeongsan 38541 , Republic of Korea.
  • Park S; New Drug Development Center , Daegu-Gyeongbuk Medical Innovation Foundation , Daegu 41061 , Republic of Korea.
  • Shrestha A; College of Pharmacy, Graduate School of Pharmaceutical Sciences , Ewha Womans University , Seoul 120-750 , Republic of Korea.
  • Jo H; College of Pharmacy , Yeungnam University , Gyeongsan 38541 , Republic of Korea.
  • Hwang SY; College of Pharmacy, Graduate School of Pharmaceutical Sciences , Ewha Womans University , Seoul 120-750 , Republic of Korea.
  • Katila P; College of Pharmacy, Graduate School of Pharmaceutical Sciences , Ewha Womans University , Seoul 120-750 , Republic of Korea.
  • Shrestha R; College of Pharmacy , Yeungnam University , Gyeongsan 38541 , Republic of Korea.
  • Nepal MR; College of Pharmacy , Yeungnam University , Gyeongsan 38541 , Republic of Korea.
  • Noh K; College of Pharmacy , Yeungnam University , Gyeongsan 38541 , Republic of Korea.
  • Kim SK; College of Pharmacy , Yeungnam University , Gyeongsan 38541 , Republic of Korea.
  • Koh WS; Laboratory Animal Center , Daegu-Gyeongbuk Medical Innovation Foundation , Daegu 41061 , Republic of Korea.
  • Kim KS; Laboratory Animal Center , Daegu-Gyeongbuk Medical Innovation Foundation , Daegu 41061 , Republic of Korea.
  • Jeon YH; Laboratory Animal Center , Daegu-Gyeongbuk Medical Innovation Foundation , Daegu 41061 , Republic of Korea.
  • Jeong TC; College of Veterinary Medicine , Kyungpook National University , Daegu 41566 , Republic of Korea.
  • Kwon Y; Laboratory Animal Center , Daegu-Gyeongbuk Medical Innovation Foundation , Daegu 41061 , Republic of Korea.
  • Lee ES; College of Pharmacy , Yeungnam University , Gyeongsan 38541 , Republic of Korea.
J Med Chem ; 62(17): 8194-8234, 2019 09 12.
Article in En | MEDLINE | ID: mdl-31398033
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Pyridines / Biphenyl Compounds / Breast Neoplasms / DNA Topoisomerases, Type II / Drug Discovery / Topoisomerase II Inhibitors / Antineoplastic Agents Limits: Animals / Female / Humans / Male Language: En Journal: J Med Chem Journal subject: QUIMICA Year: 2019 Document type: Article Country of publication:
Fulltext
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Pyridines / Biphenyl Compounds / Breast Neoplasms / DNA Topoisomerases, Type II / Drug Discovery / Topoisomerase II Inhibitors / Antineoplastic Agents Limits: Animals / Female / Humans / Male Language: En Journal: J Med Chem Journal subject: QUIMICA Year: 2019 Document type: Article Country of publication: