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The guanylate cyclase C agonist linaclotide ameliorates the gut-cardio-renal axis in an adenine-induced mouse model of chronic kidney disease.
Nanto-Hara, Fumika; Kanemitsu, Yoshitomi; Fukuda, Shinji; Kikuchi, Koichi; Asaji, Kei; Saigusa, Daisuke; Iwasaki, Tomoyuki; Ho, Hsin-Jung; Mishima, Eikan; Suzuki, Takehiro; Suzuki, Chitose; Tsukimi, Tomoya; Matsuhashi, Tetsuro; Oikawa, Yoshitsugu; Akiyama, Yukako; Kure, Shigeo; Owada, Yuji; Tomioka, Yoshihisa; Soga, Tomoyoshi; Ito, Sadayoshi; Abe, Takaaki.
Affiliation
  • Nanto-Hara F; Department of Medical Science, Tohoku University Graduate School of Biomedical Engineering, Sendai, Japan.
  • Kanemitsu Y; Department of Anatomy, Tohoku University Graduate School of Medicine, Sendai, Japan.
  • Fukuda S; Division of Nephrology, Endocrinology, and Vascular Medicine, Tohoku University Graduate School of Medicine, Sendai, Japan.
  • Kikuchi K; Laboratory of Oncology, Pharmacy Practice and Sciences, Tohoku University Graduate School of Pharmaceutical Sciences, Sendai, Japan.
  • Asaji K; Institute for Advanced Biosciences, Keio University, Tsuruoka, Japan.
  • Saigusa D; Intestinal Microbiota Project, Kanagawa Institute of Industrial Science and Technology, Kawasaki, Japan.
  • Iwasaki T; Transborder Medical Research Center, University of Tsukuba, Tsukuba, Japan.
  • Ho HJ; PRESTO, Japan Science and Technology Agency, Kawaguchi, Japan.
  • Mishima E; Division of Nephrology, Endocrinology, and Vascular Medicine, Tohoku University Graduate School of Medicine, Sendai, Japan.
  • Suzuki T; Department of Clinical Biology and Hormonal Regulation, Tohoku University Graduate School of Medicine, Sendai, Japan.
  • Suzuki C; Laboratory of Oncology, Pharmacy Practice and Sciences, Tohoku University Graduate School of Pharmaceutical Sciences, Sendai, Japan.
  • Tsukimi T; Department of Integrative Genomics, Tohoku Medical Megabank Organization, Tohoku University, Sendai, Japan.
  • Matsuhashi T; Division of Nephrology, Endocrinology, and Vascular Medicine, Tohoku University Graduate School of Medicine, Sendai, Japan.
  • Oikawa Y; Department of Medical Science, Tohoku University Graduate School of Biomedical Engineering, Sendai, Japan.
  • Akiyama Y; Division of Nephrology, Endocrinology, and Vascular Medicine, Tohoku University Graduate School of Medicine, Sendai, Japan.
  • Kure S; Division of Nephrology, Endocrinology, and Vascular Medicine, Tohoku University Graduate School of Medicine, Sendai, Japan.
  • Owada Y; Department of Medical Science, Tohoku University Graduate School of Biomedical Engineering, Sendai, Japan.
  • Tomioka Y; Division of Nephrology, Endocrinology, and Vascular Medicine, Tohoku University Graduate School of Medicine, Sendai, Japan.
  • Soga T; Division of Nephrology, Endocrinology, and Vascular Medicine, Tohoku University Graduate School of Medicine, Sendai, Japan.
  • Ito S; Institute for Advanced Biosciences, Keio University, Tsuruoka, Japan.
  • Abe T; Department of Medical Science, Tohoku University Graduate School of Biomedical Engineering, Sendai, Japan.
Nephrol Dial Transplant ; 35(2): 250-264, 2020 02 01.
Article in En | MEDLINE | ID: mdl-31411705

Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Peptides / Adenine / Renal Insufficiency, Chronic / Cardio-Renal Syndrome / Gastrointestinal Microbiome / Guanylyl Cyclase C Agonists / Guanylate Cyclase Type of study: Prognostic_studies Limits: Animals Language: En Journal: Nephrol Dial Transplant Journal subject: NEFROLOGIA / TRANSPLANTE Year: 2020 Document type: Article Affiliation country:

Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Peptides / Adenine / Renal Insufficiency, Chronic / Cardio-Renal Syndrome / Gastrointestinal Microbiome / Guanylyl Cyclase C Agonists / Guanylate Cyclase Type of study: Prognostic_studies Limits: Animals Language: En Journal: Nephrol Dial Transplant Journal subject: NEFROLOGIA / TRANSPLANTE Year: 2020 Document type: Article Affiliation country: